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  • Methotrexate and low-dose prednisolone downregulate osteoclast function by decreasing receptor activator of nuclear factor-κβ expression in monocytes from patients with early rheumatoid arthritis

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Rheumatoid arthritis
Original article
Methotrexate and low-dose prednisolone downregulate osteoclast function by decreasing receptor activator of nuclear factor-κβ expression in monocytes from patients with early rheumatoid arthritis

Authors

  • Inês Pedro Perpétuo Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal PubMed articlesGoogle scholar articles
  • Joana Caetano-Lopes Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal PubMed articlesGoogle scholar articles
  • Ana Maria Rodrigues Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal PubMed articlesGoogle scholar articles
  • Raquel Campanilho-Marques Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, PortugalDepartment of Rheumatology, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal PubMed articlesGoogle scholar articles
  • Cristina Ponte Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, PortugalDepartment of Rheumatology, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal PubMed articlesGoogle scholar articles
  • Helena Canhão EpiDoC Unit, CEDOC, NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal PubMed articlesGoogle scholar articles
  • Mari Ainola Department of Medicine, Clinicum, University of Helsinki, Helsinki, Finland PubMed articlesGoogle scholar articles
  • João Eurico Fonseca Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, PortugalDepartment of Rheumatology, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Inês Pedro Perpétuo; ines.perpetuo{at}gmail.com
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Citation

Perpétuo IP, Caetano-Lopes J, Rodrigues AM, et al
Methotrexate and low-dose prednisolone downregulate osteoclast function by decreasing receptor activator of nuclear factor-κβ expression in monocytes from patients with early rheumatoid arthritis
RMD Open 2017;3:e000365. doi: 10.1136/rmdopen-2016-000365

Publication history

  • Received September 19, 2016
  • Revision received March 22, 2017
  • Accepted March 27, 2017
  • First published July 13, 2017.
Online issue publication 
July 18, 2023

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/