Patients reaching an ID during the first 12 months of observation in ICON
| Ever ID n (%) | p Value | Percentage of time with ID during the first 12 months, mean % of subgroup (SD) | p Value | Duration from symptom onset to ID in months, median, IQR | Duration from diagnosis to ID in months, median, IQR | |
|---|---|---|---|---|---|---|
| All patients with JIA | 510 (73.4) | 40 (35) | 11.0, 7.0–15.1 | 7.9, 3.9–10.9 | ||
| Persistent oligoarthritis | 200 (79.7) | 0.062 | 46 (36) | 0.021 | 10.0, 6.0–13.0 | 6.0, 3.0–10.0 |
| Extended oligoarthritis | 42 (67.7) | 0.323 | 37 (38) | 0.592 | 14.0, 10.9–18.5 | 9.0, 6.0–13.0 |
| Polyarthritis RF negative | 144 (73.9) | 0.852 | 38 (34) | 0.583 | 11.0, 7.8–14.2 | 8.0, 4.0–11.0 |
| Polyarthritis RF positive | 9 (90.0) | 0.168 | 43 (42) | 0.769 | 17.0, 9.9–18.0 | 7.0, 6.0–12.0 |
| Psoriatic arthritis | 19 (55.9) | 0.014 | 25 (29) | 0.011 | 13.0, 5.9–17.0 | 7.0, 5.0–11.0 |
| Enthesitis-related arthritis | 41 (55.4) | 0.001 | 27 (32) | 0.002 | 15.9, 11.8–20.0 | 9.0, 3.7–12.0 |
| Systemic arthritis | 22 (88.0) | 0.078 | 57 (35) | 0.008 | 7.0, 4.0–10.0 | 5.1, 3.0–9.0 |
| Undifferentiated arthritis | 33 (75.0) | 0.767 | 44 (35) | 0.426 | 13.0, 7.0–20.0 | 7.2, 3.9–12.0 |
Significant p values (<0.05) are shown in bold, comparing the means of all patients with JIA within a category using regression analysis.
ID, inactive disease; JIA, juvenile idiopathic arthritis; RF, rheumatoid factor.