The more similar the rates in off-diagonal cells involving the same outcome measures, the closer the concordance of the outcome measures; cells for ACR50 and CDAI LDA, and ACR70 and CDAI remission are shaded as an example.
Numbers of patients available for assessment varied between parameters; to be included, a patient must have non-missing values for both outcomes.
Response rate for the second outcome was low for ACR70 and remission outcomes (ranging from 0% to 46%) in patients that did not respond to the first outcome.
ACR, American College of Rheumatology; BID, twice daily; CDAI, Clinical Disease Activity Index; HAQ-DI, Health Assessment Questionnaire-Disability Index; LDA, low disease activity; MTX, methotrexate; N, number of patients assessed at month 6; n, number of responders; SDAI, Simplified Disease Activity Index.