Diabetes | Hypertension | Cardiovascular disease | Depression | |||||
---|---|---|---|---|---|---|---|---|
Univariate OR (95% CI) | Multivariate OR (95% CI) | Univariate OR (95% CI) | Multivariate OR (95% CI) | Univariate OR (95% CI) | Multivariate OR (95% CI) | Univariate OR (95% CI) | Multivariate OR (95% CI) | |
No RA | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
All self-reported RA | 1.54*** (1.40 to 1.70) | 1.18** (1.06 to 1.32) | 1.41*** (1.46 to 1.63) | 1.19*** (1.21 to 1.27) | 1.80*** (1.65 to 1.96) | 1.52*** (1.39 to 1.67) | 1.26*** (1.14 to 1.40) | 1.07 (0.96 to 1.19) |
No RA | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Treated RA | 1.36*** (1.18 to 1.57) | 1.16 (1.00 to 1.36) | 1.41*** (1.30 to 1.53) | 1.28*** (1.17 to 1.39) | 1.63*** (1.44 to 1.85) | 1.43*** (1.25 to 1.63) | 1.06 (0.91 to 1.24) | 0.90 (0.77 to 1.06) |
No RA | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
Steroids only | 0.86 (0.12 to 6.39) | 0.63 (0.08 to 4.83) | 2.24 (0.83 to 6.07) | 1.72 (0.57 to 5.13) | 2.49 (0.74 to 8.41) | 1.61 (0.45 to 5.70) | 0.80 (0.11 to 5.97) | 0.75 (0.10 to 5.67) |
1 synthetic DMARD | 1.36** (1.13 to 1.64) | 1.19 (0.98 to 1.46) | 1.44*** (1.30 to 1.60) | 1.34*** (1.20 to 1.50) | 1.36** (1.14 to 1.62) | 1.27** (1.06 to 1.53) | 0.95 (0.77 to 1.18) | 0.81 (0.66 to 1.01) |
>1 synthetic DMARD | 1.38** (1.08 to 1.76) | 1.12 (0.86 to 1.45) | 1.36*** (1.19 to 1.55) | 1.16* (1.00 to 1.34) | 2.19*** (1.81 to 2.64) | 1.75*** (1.43 to 2.14) | 1.24 (0.97 to 1.58) | 1.04 (0.81 to 1.34) |
Biologic DMARD | 1.30 (0.63 to 2.66) | 1.24 (0.59 to 2.63) | 1.35 (0.92 to 1.98) | 1.38 (0.91 to 2.07) | 0.84 (0.37 to 1.90) | 0.83 (0.36 to 1.92) | 1.22 (0.59 to 2.49) | 1.00 (0.48 to 2.06) |
Multivariate: adjusted for age, sex, ethnicity, deprivation quintile, smoking, body mass index and alcohol intake.
*p<0.05; **p<0.01; ***p<0.001.
DMARD, disease-modifying antirheumatic drug; RA, rheumatoid arthritis.