All n=60 | Subgroup for Analysis of predictors of outcome | |||
---|---|---|---|---|
Included n=41 | Excluded n=19 | p Value | ||
Age, mean (SD) | 46 (14) | 45 (15) | 48 (11) | 0.4 |
Female | 39 (65%) | 27 (66%) | 12 (63%) | 0.8 |
Symptom duration, months | 9 (4–17) | 9 (4–18) | 8 (4–17) | 0.8 |
ACPA positive | 4 (7%) | 3 (7%) | 1 (5%) | 1.0 |
Early Morning Stiffness ≥60 min | 31 (52%) | 19 (46%) | 12 (63%) | 0.3 |
RAI SJC44 | 3 (2–6)a 2 (1–4)a | 3 (2–6) 2 (1–5) | 2 (1–3)a 2 (1–3)a | 0.1 0.7 |
CRP, mg/L | 7 (0–23) | 6 (0–22) | 10 (0–27) | 0.4 |
Patient VASDA, mm | 43 (25–66)a+b | 45 (25–68)b | 34 (17–63)a | 0.7 |
DAS-CRP | 2.3 (1.6–2.9)b+c | 2.3 (1.8–2.9)b | 1.8 (1.3–2.5)c | 0.2 |
HAQ | 0.3 (0.1–0.9)a+d | 0.3 (0.1–0.9)d | 0.6 (0.1–1.1)a | 0.9 |
US of 26 joints at baseline: total GS score | 9 (5–16)e | 9 (5–17) | NAe | NA |
Total PD score | 1 (0–2)e | 1 (0–2) | NAe | NA |
Number of joints with GS≥ grade 2 Number of joints with PD≥ grade 1 | 2 (1–5)e 1 (0–1)e | 2 (1–5) 1 (0–1) | NAe | NA |
Fulfilment of 2010 ACR/EULAR RA criteria with joint involvement determined clinically or by GS≥ grade 2 and/or PD≥ grade 1 | 4/42 (10%) | 4 (10%) | NAe | NA |
Radiographic erosion in the hands and/or feet | 4/55 (7%) | 3 (7%) | 1 (7%)f | 1.0 |
Missing data in a12, b8, c13, d6, e18 and f5 cases.
ACPA, anti-cyclic citrullinated protein antibody; ACR, American College of Rheumatology; CRP, C reactive protein; DAS-CRP, disease activity score; EULAR, European League Against Rheumatism; GS, grey scale; HAQ, Health Assessment Questionnaire; NA, not applicable (summary statistics not performed due to insufficient data); PD, power Doppler activity; RA, rheumatoid arthritis;RAI, Ritchie articular index; SJC44, swollen joint count of 44 joints; US, ultrasound; VASDA, visual analogue scale disease activity assessment.