Characteristics of participants at baseline
| All (n=100) | Māori or Pacific ancestry (n=50) | European ancestry (n=50) | p Value | |
|---|---|---|---|---|
| Age, years | 28 (9) | 26 (8) | 31 (10) | 0.0026 |
| Male sex, n (%) | 29 (29%) | 13 (26%) | 16 (32%) | 0.66 |
| Body mass index, kg/m2 | 26 (5) | 27 (5) | 25 (5) | 0.14 |
| Waist circumference, cm | 80 (25) | 81 (23) | 79 (27) | 0.64 |
| Systolic blood pressure, mm Hg | 121 (12) | 123 (11) | 120 (13) | 0.34 |
| Diastolic blood pressure, mm Hg | 70 (9) | 68 (8) | 71 (9) | 0.13 |
| Serum urate, mmol/L | 0.31 (0.07) | 0.32 (0.07) | 0.29 (0.08) | 0.044 |
| Serum urate, mg/dL | 5.2 (1.2) | 5.3 (1.2) | 4.8 (1.3) | 0.044 |
| Serum sodium, mmol/L (reference range 135–145 mmol/L) | 138 (2) | 138 (2) | 138 (2) | 0.68 |
| Serum potassium, mmol/L (reference range 3.5–5.2 mmol/L) | 3.8 (0.3) | 3.7 (0.2) | 3.9 (0.3) | 0.027 |
| Serum creatinine, µmol/L (female reference range 45–90 µmol/L, male reference range 60–105 µmol/L) | 74 (13) | 74 (12) | 74 (13) | 0.98 |
| Fractional excretion of urate (%) | 6.3 (2.2) | 6.1 (2.2) | 6.5 (2.2) | 0.40 |
| Fractional excretion of sodium (%) | 0.4 (0.3) | 0.4 (0.3) | 0.4 (0.2) | 0.56 |
| Fractional excretion of potassium (%) | 13 (17) | 13 (23) | 12 (8) | 0.83 |
| SLC2A9 rs11942223 protective C allele present, n (%) | 30 (30%) | 11 (22%) | 19 (38%) | 0.13 |
| SLC2A9 rs13129697 protective G allele present, n (%) | 50 (50%) | 29 (58%) | 21 (42%) | 0.16 |
| SLC22A11 rs2078267 protective T allele present, n (%) | 53 (53%) | 17 (34%) | 36 (72%) | 0.0003 |
Unless stated, data are presented as mean (SD).