Risk of bias of randomised controlled trials
| Random sequence generation (selection bias) | Allocation concealment (selection bias) | Blinding of participants and personnel (performance bias) | Blinding of outcome assessment (detection bias) | Incomplete outcome data (attrition bias) | Selective reporting (reporting bias) | |
| Jover et al8 | L | U | L | U | L | L |
| Salvarani et al47 | L | L | L | L | L | U |
| Cimmino et al48 | L | U | L | L | L | U |
| Seror et al56 | L | L | L | L | H | U |
H, high risk of bias; L, lower risk of bias; U, unclear risk of bias.