Table 2

Association between biomarkers, radiographic damage and change and CRP

C1MC5MC6MVICMCRP
CRPρ
p
N
0.75
<0.0001
120
−0.01
ns
114
0.73
<0.0001
118
0.37
<0.0001
120
Baseline mSASSSρ
p
N
0.10
ns
122
−0.07
ns
116
−0.09
ns
120
0.02
ns
122
−0.02
ns
120
2 year mSASSS changeρ
p
N
0.22
0.013
122
−0.07
ns
116
0.08
ns
120
−0.04
ns
122
0.22
0.017
120
  • Values are Spearman’ s correlation coefficients.

  • CRP, C-reactive protein; C1M, C5M and C6M, MMP-mediated degradation of type I, V and VI collagen, respectively; mSASSS, modified Stoke Ankylosing Spondylitis Spine Score; MMP, matrix metalloproteinase; VICM, citrullinated and MMP-degraded vimentin, NS, non-significant