Sjogren’s syndrome: An update on clinical, basic and diagnostic therapeutic aspects

https://doi.org/10.1016/j.jaut.2012.01.006Get rights and content

Abstract

The 11th International Symposium for Sjogren’s syndrome was held in Athens, Greece in September 2011. This symposia is part of a long series of meetings that have attempted to meet the needs of both scientists and physicians in improving the healthcare of their patients with Sjogren’s syndrome. Sjogren’s syndrome affects almost 0.5% of the general population and is second only to rheumatoid arthritis amongst the systemic autoimmune diseases. More importantly, it has daily implications for the millions of sufferers around the world. The goal of this meeting, which included nearly 200 abstracts and invited lectures, was to address the critical needs in the clinical practice of Sjogren’s syndrome. This volume is a composite of select papers that were presented at this meeting and attempts to provide a critical overview of clinical and basic science. The volume includes a variety of themes and, importantly, raises issues that are still unresolved but which are important in our future diagnostic and therapeutic efforts.

Highlights

► Sjögren’s syndrome affects around 0.5% of the general adult population. ► This issue of Journal of Autoimmunity contains papers devoted to the Pathophysiology, diagnosis and treatment of the disease. ► Major clinical achievements, regarding the disease, include classification criteria and clinical outcome. ► The implementation of molecular immunology, shed light into the central role of epithelial cells in the pathogenesis of the disease. Therefore the etiologic name of the disease is “autoimmune epithelitis”.

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