A new superfamily of cell surface proteins related to the nerve growth factor receptor

S Mallett; A N Barclay

doi:10.1016/0167-5699(91)90033-P

A new superfamily of cell surface proteins related to the nerve growth factor receptor

Immunol Today. 1991 Jul;12(7):220-3. doi: 10.1016/0167-5699(91)90033-P.

Authors

S Mallett¹, A N Barclay

Affiliation

¹ MRC Cellular Immunology Unit, Sir William Dunn School of Pathology, University of Oxford, UK.

PMID: 1653571
DOI: 10.1016/0167-5699(91)90033-P

Abstract

In this article Susan Mallett and Neil Barclay discuss the molecular and functional features of a new superfamily of membrane proteins defined by the presence of cysteine-rich motifs originally identified in the low-affinity nerve growth factor receptor. This superfamily includes two lymphocyte proteins of unknown function and two receptors for tumor necrosis factor.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Amino Acid Sequence
Animals
Humans
Membrane Proteins / genetics
Molecular Sequence Data
Nerve Growth Factors
Receptors, Cell Surface / genetics*
Receptors, Nerve Growth Factor
Receptors, Tumor Necrosis Factor
Sequence Homology, Nucleic Acid
Tumor Necrosis Factor-alpha

Substances

Membrane Proteins
Nerve Growth Factors
Receptors, Cell Surface
Receptors, Nerve Growth Factor
Receptors, Tumor Necrosis Factor
Tumor Necrosis Factor-alpha