Impact of hypertension on stroke

Curr Atheroscler Rep. 2011 Aug;13(4):298-305. doi: 10.1007/s11883-011-0187-y.

Abstract

Hypertension is the single most important risk factor for all types of stroke: ischemic stroke, intracerebral hemorrhage, and aneurysmal subarachnoid hemorrhage. Epidemiologic studies over the past 30 years have demonstrated a dramatic reduction in the incidence and mortality of all stroke types with good control of hypertension, and it appears that all effective antihypertensive agents have similar efficacy in their ability to reduce stroke risk. In addition, it appears that acute treatment of hypertension in the setting of intracerebral hemorrhage and subarachnoid hemorrhage is beneficial, but it is still uncertain in the setting of ischemic stroke what level of blood pressure will result in the best possible outcome.

Publication types

  • Review

MeSH terms

  • Angiotensin Receptor Antagonists / therapeutic use
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Antihypertensive Agents / therapeutic use
  • Brain Ischemia / complications
  • Brain Ischemia / etiology*
  • Cerebrovascular Circulation
  • Humans
  • Hypertension / complications*
  • Hypertension / drug therapy
  • Intracranial Hemorrhage, Hypertensive / complications
  • Intracranial Hemorrhage, Hypertensive / etiology
  • Practice Guidelines as Topic
  • Stroke / etiology*
  • Stroke / prevention & control*
  • Subarachnoid Hemorrhage / complications
  • Subarachnoid Hemorrhage / etiology

Substances

  • Angiotensin Receptor Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Antihypertensive Agents