[HTML][HTML] Interleukin 12 a key immunoregulatory cytokine in infection applications

T Hamza, JB Barnett, B Li - International journal of molecular sciences, 2010 - mdpi.com
Interleukin 12 (termed IL-12p70 and commonly designated IL-12) is an important
immunoregulatory cytokine that is produced mainly by antigen-presenting cells. The …

Developmental immunotoxicity of atrazine in rodents

AM Rowe, KM Brundage… - Basic & clinical …, 2008 - Wiley Online Library
There is a substantial literature reporting that the developing immune system is more
sensitive to toxic insult and that the measurable phenotype resulting from prenatal/neonatal …

Advances in polyelectrolyte multilayer nanofilms as tunable drug delivery systems

B Jiang, JB Barnett, B Li - Nanotechnology, science and …, 2009 - Taylor & Francis
There has been considerable interest in polyelectrolyte multilayer nanofilms, which have a
variety of applications ranging from optical and electrochemical materials to biomedical …

Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells

TA Stueckle, Y Lu, ME Davis, L Wang, BH Jiang… - Toxicology and applied …, 2012 - Elsevier
Chronic arsenic exposure remains a human health risk; however a clear mode of action to
understand gene signaling-driven arsenic carcinogenesis is currently lacking. This study …

Prenatal cadmium exposure alters postnatal immune cell development and function

ML Hanson, I Holásková, M Elliott, KM Brundage… - Toxicology and applied …, 2012 - Elsevier
Cadmium (Cd) is generally found in low concentrations in the environment due to its
widespread and continual use, however, its concentration in some foods and cigarette …

[HTML][HTML] Gene disruption of the calcium channel Orai1 results in inhibition of osteoclast and osteoblast differentiation and impairs skeletal development

LJ Robinson, S Mancarella, D Songsawad… - Laboratory …, 2012 - Elsevier
Calcium signaling plays a central role in the regulation of bone cells, although uncertainty
remains with regard to the channels involved. In previous studies, we determined that the …

Improving the risk assessment of lipophilic persistent environmental chemicals in breast milk

GM Lehmann, MA Verner, B Luukinen… - Critical Reviews in …, 2014 - Taylor & Francis
Lipophilic persistent environmental chemicals (LPECs) have the potential to accumulate
within a woman's body lipids over the course of many years prior to pregnancy, to partition …

Prenatal cadmium exposure produces persistent changes to thymus and spleen cell phenotypic repertoire as well as the acquired immune response

I Holásková, M Elliott, ML Hanson, R Schafer… - Toxicology and applied …, 2012 - Elsevier
Cadmium (Cd) is a common environmental contaminant. Adult exposure to Cd alters the
immune system, however, there are limited studies on the effects of prenatal exposure to Cd …

Prenatal cadmium exposure dysregulates sonic hedgehog and Wnt/β-catenin signaling in the thymus resulting in altered thymocyte development

ML Hanson, KM Brundage, R Schafer, JC Tou… - Toxicology and applied …, 2010 - Elsevier
Cadmium (Cd) is both an environmental pollutant and a component of cigarette smoke.
Although evidence demonstrates that adult exposure to Cd causes changes in the immune …

The role of calcium release activated calcium channels in osteoclast differentiation

Y Zhou, TL Lewis, LJ Robinson… - Journal of cellular …, 2011 - Wiley Online Library
Osteoclasts are specialized macrophage derivatives that secrete acid and proteinases to
mobilize bone for mineral homeostasis, growth, and replacement or repair. Osteoclast …