[HTML][HTML] NGF and its receptors in the regulation of inflammatory response

G Minnone, F De Benedetti… - International journal of …, 2017 - mdpi.com
There is growing interest in the complex relationship between the nervous and immune
systems and how its alteration can affect homeostasis and result in the development of …

[HTML][HTML] Interleukin-1β and interleukin-6 in arthritis animal models: roles in the early phase of transition from acute to chronic inflammation and relevance for human …

G Ferraccioli, L Bracci-Laudiero, S Alivernini… - Molecular …, 2010 - Springer
Tumor necrosis factor-α (TNF-α) is the major target of the therapeutic approach in
rheumatoid arthritis. A key issue in the approach to chronic arthritis is the understanding of …

[HTML][HTML] Nerve growth factor is an autocrine survival factor for memory B lymphocytes

M Torcia, L Bracci-Laudiero, M Lucibello, L Nencioni… - Cell, 1996 - cell.com
Production of nerve growth factor (NGF) was assessed in cultures of human T and B
lymphocytes and macrophages. NGF was constitutively produced by B cells only, which also …

Human CD4+ T cell clones produce and release nerve growth factor and express high-affinity nerve growth factor receptors

A Lambiase, L Bracci-Laudiero, S Bonini… - Journal of Allergy and …, 1997 - Elsevier
Background: Increasing evidence shows that nerve growth factor (NGF) plays a role in the
complex and fascinating linkage between the nervous and the immune systems due to its …

Expression and function of nerve growth factor and nerve growth factor receptor on cultured keratinocytes

C Pincelli, C Sevignani, R Manfredini, A Grande… - Journal of Investigative …, 1994 - Elsevier
Keratinocytes, a key cellular component both for homeostasis and pathophysiologic
processes of the skin, secrete a number of cytokines and are stimulated by several growth …

Human monocyte/macrophages activate by exposure to LPS overexpress NGF and NGF receptors

MC Caroleo, N Costa, L Bracci-Laudiero… - Journal of …, 2001 - Elsevier
Monocyte/macrophages (M/M) represent the main cellular component of the immune system
involved in the inflammatory response. In the present study we investigate whether NGF is …

Nerve growth factor downregulates inflammatory response in human monocytes through TrkA

G Prencipe, G Minnone, R Strippoli… - The Journal of …, 2014 - journals.aai.org
Nerve growth factor (NGF) levels are highly increased in inflamed tissues, but their role is
unclear. We show that NGF is part of a regulatory loop in monocytes: inflammatory stimuli …

[HTML][HTML] Prevalence of antibodies to SARS-CoV-2 in Italian adults and associated risk factors

A Vena, M Berruti, A Adessi, P Blumetti… - Journal of clinical …, 2020 - mdpi.com
We aimed to assess the prevalence of and factors associated with anti-severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) positivity in a large population of adult …

Amplification of the response to Toll‐like receptor ligands by prolonged exposure to interleukin‐6 in mice: implication for the pathogenesis of macrophage activation …

R Strippoli, F Carvello, R Scianaro… - Arthritis & …, 2012 - Wiley Online Library
Objective To investigate whether prolonged exposure to interleukin‐6 (IL‐6) affects the
inflammatory response induced by Toll‐like receptor (TLR) ligands. Methods IL‐6 …

NGF in early embryogenesis, differentiation, and pathology in the nervous and immune systems

L Bracci-Laudiero, ME De Stefano - Neurotoxin Modeling of Brain …, 2016 - Springer
The physiology of NGF is extremely complex, and although the study of this neurotrophin
began more than 60 years ago, it is far from being concluded. NGF, its precursor molecule …