User profiles for "author:Matteo Vecellio"
 | Matteo VecellioUniversity of Oxford Verified email at ndorms.ox.ac.uk Cited by 1536 |
[HTML][HTML] The IL-17/IL-23 axis and its genetic contribution to psoriatic arthritis
M Vecellio, VX Hake, C Davidson, MC Carena… - Frontiers in …, 2021 - frontiersin.org
Psoriatic arthritis (PsA) is a chronic inflammatory disease belonging to the family of
spondyloarthropathies (SpA). PsA commonly aggravates psoriasis of the skin and frequently …
spondyloarthropathies (SpA). PsA commonly aggravates psoriasis of the skin and frequently …
[HTML][HTML] Clinical trials supporting the role of the IL-17/IL-23 axis in axial spondyloarthritis
A Ceribelli, F Motta, M Vecellio, N Isailovic… - Frontiers in …, 2021 - frontiersin.org
The term spondyloarthritis (SpA) encompasses a heterogeneous group of inflammatory
musculoskeletal diseases with several common genetic background and clinical features …
musculoskeletal diseases with several common genetic background and clinical features …
[PDF][PDF] Mutations in the small GTPase gene RAB39B are responsible for X-linked mental retardation associated with autism, epilepsy, and macrocephaly
M Giannandrea, V Bianchi, ML Mignogna, A Sirri… - The American Journal of …, 2010 - cell.com
Human Mental Retardation (MR) is a common and highly heterogeneous pediatric disorder
affecting around 3% of the general population; at least 215 X-linked MR (XLMR) conditions …
affecting around 3% of the general population; at least 215 X-linked MR (XLMR) conditions …
Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy
S Picaud, O Fedorov, A Thanasopoulou, K Leonards… - Cancer research, 2015 - AACR
The histone acetyltransferases CBP/p300 are involved in recurrent leukemia-associated
chromosomal translocations and are key regulators of cell growth. Therefore, efforts to …
chromosomal translocations and are key regulators of cell growth. Therefore, efforts to …
The role of epigenetics and immunological imbalance in the etiopathogenesis of psoriasis and psoriatic arthritis
L Frischknecht, M Vecellio… - Therapeutic Advances in …, 2019 - journals.sagepub.com
Psoriasis (Ps) and psoriatic arthritis (PsA) represent a clinical and immunopathogenic
continuum, called psoriatic disease, cumulatively affecting approximately 3% of the general …
continuum, called psoriatic disease, cumulatively affecting approximately 3% of the general …
CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses
A Hammitzsch, C Tallant, O Fedorov… - Proceedings of the …, 2015 - National Acad Sciences
Th17 responses are critical to a variety of human autoimmune diseases, and therapeutic
targeting with monoclonal antibodies against IL-17 and IL-23 has shown considerable …
targeting with monoclonal antibodies against IL-17 and IL-23 has shown considerable …
A case of psoriatic arthritis triggered by SARS-CoV-2 infection
L Novelli, F Motta, A Ceribelli, GM Guidelli… - …, 2021 - academic.oup.com
DEAR EDITOR, Several autoimmune/autoinflammatory phenomena have been described
during the new coronavirus SARS-CoV-2 pandemic, including cytokine storm/macrophage …
during the new coronavirus SARS-CoV-2 pandemic, including cytokine storm/macrophage …
The histone acetylase activator pentadecylidenemalonate 1b rescues proliferation and differentiation in the human cardiac mesenchymal cells of type 2 diabetic …
M Vecellio, F Spallotta, S Nanni, C Colussi… - Diabetes, 2014 - Am Diabetes Assoc
This study investigates the diabetes-associated alterations present in cardiac mesenchymal
cells (CMSC) obtained from normoglycemic (ND-CMSC) and type 2 diabetic patients (D …
cells (CMSC) obtained from normoglycemic (ND-CMSC) and type 2 diabetic patients (D …
The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression
Objectives To identify the functional basis for the genetic association of single nucleotide
polymorphisms (SNP), upstream of the RUNX3 promoter, with ankylosing spondylitis (AS) …
polymorphisms (SNP), upstream of the RUNX3 promoter, with ankylosing spondylitis (AS) …
An ankylosing spondylitis-associated genetic variant in the IL23R-IL12RB2 intergenic region modulates enhancer activity and is associated with increased Th1-cell …
AR Roberts, M Vecellio, L Chen, A Ridley… - Annals of the …, 2016 - ard.bmj.com
Objectives To explore the functional basis for the association between ankylosing
spondylitis (AS) and single-nucleotide polymorphisms (SNPs) in the IL23R-IL12RB2 …
spondylitis (AS) and single-nucleotide polymorphisms (SNPs) in the IL23R-IL12RB2 …