[HTML][HTML] S100A8 & S100A9: Alarmin mediated inflammation in tendinopathy

LAN Crowe, M McLean, SM Kitson, EG Melchor… - Scientific reports, 2019 - nature.com
Abstract Alarmins S100A8 and S100A9 are endogenous molecules released in response to
environmental triggers and cellular damage. They are constitutively expressed in immune …

[HTML][HTML] MicroRNA29a treatment improves early tendon injury

AE Watts, NL Millar, J Platt, SM Kitson, M Akbar… - Molecular Therapy, 2017 - cell.com
Tendon injuries (tendinopathies) are common in human and equine athletes and
characterized by dysregulated collagen matrix, resulting in tendon damage. We have …

Targeting danger molecules in tendinopathy: the HMGB1/TLR4 axis

M Akbar, DS Gilchrist, SM Kitson, B Nelis… - RMD open, 2017 - rmdopen.bmj.com
Objectives To seek evidence of the danger molecule, high-mobility group protein B1
(HMGB1) expression in human tendinopathy and thereafter, to explore mechanisms where …

[PDF][PDF] Brief report: proatherogenic cytokine microenvironment in the aortic adventitia of patients with rheumatoid arthritis

A Ahmed, I Hollan, SA Curran, SM Kitson… - Arthritis & …, 2016 - Wiley Online Library
Objective Patients with rheumatoid arthritis (RA) are at increased risk of developing
cardiovascular disease (CVD) via mechanisms that have not yet been defined. Inflammatory …

Co‐opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice

LM MacLellan, J Montgomery, F Sugiyama… - Arthritis & …, 2011 - Wiley Online Library
Objective Cells of the monocytic lineage play fundamental roles in the regulation of health,
ranging from the initiation and resolution of inflammation to bone homeostasis. In …

GPCR production in a novel yeast strain that makes cholesterol-like sterols

SM Kitson, W Mullen, RJ Cogdell, RM Bill, NJ Fraser - Methods, 2011 - Elsevier
The activities of many mammalian membrane proteins including G-protein coupled
receptors are cholesterol-dependent. Unlike higher eukaryotes, yeast do not make …

Rheumatoid arthritis patients have a pro-atherogenic cytokine microenvironment in the aortic adventitia

A Ahmed, I Hollan, SA Curran, SM Kitson… - Arthritis and …, 2016 - eprints.gla.ac.uk
Background: People with rheumatoid arthritis (RA) are at increased risk of developing
cardiovascular disease (CVD) via as yet, poorly defined mechanisms. Inflammatory …

[CITATION][C] Brief Report Arthritis & Rheumatology

MD Ivana Hollan, SM Kitson, MD Aukrust - 2016