Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with …
D van der Heijde, JCC Wei, M Dougados, P Mease… - The Lancet, 2018 - thelancet.com
Background Biological disease-modifying anti-rheumatic drugs (bDMARDs) are
recommended for radiographic axial spondyloarthritis, otherwise known as ankylosing …
recommended for radiographic axial spondyloarthritis, otherwise known as ankylosing …
[HTML][HTML] Baricitinib in patients with inadequate response or intolerance to conventional synthetic DMARDs: results from the RA-BUILD study
M Dougados, D van der Heijde, YC Chen… - Annals of the …, 2017 - ard.bmj.com
Background Baricitinib is an oral, reversible, selective Janus kinase 1 and 2 inhibitor.
Methods In this phase III, double-blind 24-week study, 684 biologic disease-modifying …
Methods In this phase III, double-blind 24-week study, 684 biologic disease-modifying …
Three multicenter, randomized, double‐blind, placebo‐controlled studies evaluating the efficacy and safety of ustekinumab in axial spondyloarthritis
A Deodhar, LS Gensler, J Sieper, M Clark… - Arthritis & …, 2019 - Wiley Online Library
Objective To evaluate the efficacy and safety of ustekinumab in 3 randomized, placebo‐
controlled studies in patients with axial spondyloarthritis (SpA). Studies 1 and 2 included …
controlled studies in patients with axial spondyloarthritis (SpA). Studies 1 and 2 included …
[HTML][HTML] Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy
To investigate whether altered energy metabolism induces the Warburg effect and results in
tumor malignancy, the respiratory enzyme citrate synthase (CS) was examined, silenced …
tumor malignancy, the respiratory enzyme citrate synthase (CS) was examined, silenced …
[HTML][HTML] Recommendations for psoriatic arthritis management: a joint position paper of the Taiwan Rheumatology Association and the Taiwanese Association for …
In Taiwan, the incidence and prevalence of psoriatic arthritis (PsA) have risen significantly in
recent years. Moreover, data from the Taiwan National Health Insurance Research …
recent years. Moreover, data from the Taiwan National Health Insurance Research …
Cumulative immunosuppressant exposure is associated with diversified cancer risk among 14 832 patients with systemic lupus erythematosus: a nested case–control …
Objectives. Immunosuppressive therapy is necessary to alter the natural course of SLE.
However, immunosuppressant-related cancer risk is a major concern. The aim of this study …
However, immunosuppressant-related cancer risk is a major concern. The aim of this study …
Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences
HM Lai, CJ Chen, BYJ Su, YC Chen, SF Yu… - …, 2012 - academic.oup.com
Objective. To explore the causal relationship between gout and Type 2 diabetes based on
genetic evidence and national outpatient database. Methods. Twenty male gout patients …
genetic evidence and national outpatient database. Methods. Twenty male gout patients …
The impact of long-term biologics/target therapy on bone mineral density in rheumatoid arthritis: a propensity score-matched analysis
JF Chen, CY Hsu, SF Yu, CH Ko, WC Chiu… - …, 2020 - academic.oup.com
Objectives To investigate changes in BMD in RA patients receiving 3-year
biological/targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARD) or …
biological/targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARD) or …
[HTML][HTML] Effects of diet control and telemedicine-based resistance exercise intervention on patients with obesity and knee osteoarthritis: a randomized control trial
This study investigated the effects of home-based nutritional and telemedicine-based
resistance exercise interventions on improving body composition, blood biochemistry, and …
resistance exercise interventions on improving body composition, blood biochemistry, and …
Adherence to hydroxychloroquine improves long-term survival of patients with systemic lupus erythematosus
Objectives HCQ, which is known to decrease SLE activity, may have a protective effect on
survival, but this has not been proven in Asia. This study aimed to determine whether HCQ …
survival, but this has not been proven in Asia. This study aimed to determine whether HCQ …