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  • Suramin increases cartilage proteoglycan accumulation in vitro and protects against joint damage triggered by papain injection in mouse knees in vivo

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Original article
Suramin increases cartilage proteoglycan accumulation in vitro and protects against joint damage triggered by papain injection in mouse knees in vivo

Authors

  • Laura-An Guns Department of Development and Regeneration, Laboratory of Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Silvia Monteagudo Department of Development and Regeneration, Laboratory of Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Maryna Kvasnytsia Tissue Engineering Unit, Department of Development and Regeneration, Skeletal Biology and Engineering Research Center, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Greet Kerckhofs Tissue Engineering Unit, Department of Development and Regeneration, Skeletal Biology and Engineering Research Center, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Jennifer Vandooren Department of Microbiology and Immunology, Laboratory of Immunobiology (Rega Institute), Leuven, Belgium PubMed articlesGoogle scholar articles
  • Ghislain Opdenakker Department of Microbiology and Immunology, Laboratory of Immunobiology (Rega Institute), Leuven, Belgium PubMed articlesGoogle scholar articles
  • Rik J Lories Department of Development and Regeneration, Laboratory of Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, Leuven, Belgium Division of Rheumatology, University Hospitals Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Frederic Cailotto Department of Development and Regeneration, Laboratory of Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, Leuven, Belgium CNRS - Université de Lorraine, UMR7365, Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Biopôle de l’Université de Lorraine, Campus Biologie-Santé, Vandoeuvre-Lès-Nancy, France PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Rik J Lories; rik.lories{at}uz.kuleuven.be
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Citation

Guns L, Monteagudo S, Kvasnytsia M, et al
Suramin increases cartilage proteoglycan accumulation in vitro and protects against joint damage triggered by papain injection in mouse knees in vivo
RMD Open 2017;3:e000604. doi: 10.1136/rmdopen-2017-000604

Publication history

  • Received October 23, 2017
  • Accepted November 6, 2017
  • First published November 30, 2017.
Online issue publication 
July 06, 2018

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/