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Original article
Osteoporosis in psoriatic arthritis: a cross-sectional study of an outpatient clinic population
  1. Agnete Malm Gulati1,2,
  2. Brigitte Michelsen2,3,
  3. Andreas Diamantopoulos4,
  4. Berit Grandaunet1,
  5. Øyvind Salvesen5,
  6. Arthur Kavanaugh6,
  7. Mari Hoff1,2,7 and
  8. Glenn Haugeberg2,4
  1. 1 Department of Rheumatology, St. Olavs Hospital, Trondheim, Norway
  2. 2 Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway
  3. 3 Department of Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway
  4. 4 Department of Rheumatology, Martina Hansens Hospital, Bærum, Norway
  5. 5 Unit for Applied Clinical Research, Norwegian University of Science and Technology, Trondheim, Norway
  6. 6 Department of Rheumatology, Allergy and Immunology, University of California San Diego, San Diego, California, USA
  7. 7 Department of of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway
  1. Correspondence to Agnete MalmGulati; agnete.m.gulati{at}


Background The risk of osteoporosis in patients with psoriatic arthritis (PsA) still remains unclear. The aim of this study was to investigate bone mineral density (BMD) at the hip and lumbar spine measured by dual-energy X-ray absorptiometry in patients with PsA.

Methods From an outpatient clinic in southern Norway, 140 patients with PsA were consecutively recruited and assessed for osteoporosis as part of a prospective study from January 2013 to May 2014. An extensive data collection was performed including demographic data and measures reflecting disease activity and health status.

Results Mean age was 52.4 years and 71 (50.7%) were women. Median disease duration was 7.8 years. The proportion of patients with low BMD (defined as Z score≤−1.0 SD) was comparable to the expected value of 16%, according to the normal distribution of the Z score in the population. Osteoporosis was only found in 6.4% (95% CI3% to 11%) of the patients. No significant associations were found between BMD and disease activity measures.

Conclusion The prevalence of PsA patients with osteoporosis or low BMD was low and in the range seen in the reference population. This supports that patients with PsA are not at high risk for osteoporosis compared with the general population. Therefore, clinicians may follow the general population guidelines for monitoring of osteoporosis for patients with PsA.

  • psoriatic arthritis
  • bone mineral density
  • osteoporosis

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  • Contributors GH and MH: conception, collection of data, planning and design, statistical analysis, interpretation of data and writing. AMG: statistical analyses, interpretation of data and writing. BM: collection of data and writing. ØS: statistical analyses and writing. AK and BHG: interpretation of data and writing. AD: collection of data, interpretation of data and writing. 

  • Funding statement The study was funded by The Liaison Committee between the Central Norway Regional Health Authority (RHA) and the Norwegian University of Science and Technology (NTNU).

  • Competing interests None declared.

  • Patient consent Not required.

  • Ethics approval Regional Committee for Medical Research Ethics in South-Eastern Norway (REK number: 2012/101).

  • Provenance and peer review Not commissioned; externally peer reviewed.

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