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Autoantigen TRIM21/Ro52 is expressed on the surface of antigen-presenting cells and its enhanced expression in Sjögren’s syndrome is associated with B cell hyperactivity and type I interferon activity

Authors

  • Maarten R Hillen Centre for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the NetherlandsDepartment of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands PubMed articlesGoogle scholar articles
  • Katia Urso GSK Immunology Network and Adaptive Immunity Research Unit, GlaxoSmithKline, Stevenage, UK PubMed articlesGoogle scholar articles
  • Emma Koppe GSK Immunology Network and Adaptive Immunity Research Unit, GlaxoSmithKline, Stevenage, UK PubMed articlesGoogle scholar articles
  • Ana Pinheiro Lopes Centre for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the NetherlandsDepartment of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands PubMed articlesGoogle scholar articles
  • Sofie L M Blokland Centre for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the NetherlandsDepartment of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands PubMed articlesGoogle scholar articles
  • Aridaman Pandit Centre for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the NetherlandsDepartment of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands PubMed articlesGoogle scholar articles
  • Tom Slocombe GSK Immunology Network and Adaptive Immunity Research Unit, GlaxoSmithKline, Stevenage, UK PubMed articlesGoogle scholar articles
  • André van Maurik Clinical Pharmacology and Experimental Medicine, GlaxoSmithKline, Stevenage, UK PubMed articlesGoogle scholar articles
  • Joel A G van Roon Centre for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the NetherlandsDepartment of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands PubMed articlesGoogle scholar articles
  • Timothy R D J Radstake Centre for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the NetherlandsGSK Immunology Network and Adaptive Immunity Research Unit, GlaxoSmithKline, Stevenage, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Joel AG van Roon; j.vanroon{at}umcutrecht.nl
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Citation

Hillen MR, Urso K, Koppe E, et al
Autoantigen TRIM21/Ro52 is expressed on the surface of antigen-presenting cells and its enhanced expression in Sjögren’s syndrome is associated with B cell hyperactivity and type I interferon activity

Publication history

  • Received January 15, 2020
  • Revision received April 10, 2020
  • Accepted May 19, 2020
  • First published June 15, 2020.
Online issue publication 
June 15, 2020

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