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Effects of physical exercise and body weight on disease-specific outcomes of people with rheumatic and musculoskeletal diseases (RMDs): systematic reviews and meta-analyses informing the 2021 EULAR recommendations for lifestyle improvements in people with RMDs
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  • Published on:
    Clarification and suggestion to Gwinnutt and colleagues

    I would like to congratulate and thank you the authors of this insightful publication on rheumatic and musculoskeletal disease. As an author of an included study, I would like to present a clarification and suggestion to Gwinnutt and colleagues regarding this review article.

    Our study, listed as reference 141 of this review 1, was included as a study on the effect of muscle strengthening exercise in patients with rheumatoid arthritis in this review, perhaps it was not precise. This study was an experiment investigating the effect of nerve mobilization exercise in patients with rheumatoid arthritis indeed. Nerve mobilization exercise is a specific exercise for normalizing the mechanical sensitivity and promoting the metabolism of the neural tissue so that pain sensitivity of the neural tissue could be reduced 2,3. This exercise does not involve resistance training, it is usually considered as stretching, mobilization or physical exercise therapy instead.

    Two studies have been published on the effectiveness of nerve mobilization exercise on pain control in patients with rheumatoid arthritis 1,4. In addition, three randomized controlled trials have been published to show the effects of nerve mobilization on pain sensitivity in patients with hand osteoarthritis 5–7. Therefore, Gwinnutt and colleagues may consider adding a subgroup analysis on the effectiveness of nerve mobilization exercise on pain control in patients with rheumatoid arthritis or osteoarthritis...

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    Conflict of Interest:
    None declared.