RT Journal Article SR Electronic T1 Undifferentiated connective tissue disease: state of the art on clinical practice guidelines JF RMD Open JO RMD Open FD EULAR SP e000786 DO 10.1136/rmdopen-2018-000786 VO 4 IS Suppl 1 A1 Margarida Antunes A1 Carlo Alberto Scirè A1 Rosaria Talarico A1 Tobias Alexander A1 Tadej Avcin A1 Chiara Belocchi A1 Andrea Doria A1 Franco Franceschini A1 Ilaria Galetti A1 Marcello Govoni A1 Eric Hachulla A1 David Launay A1 Gemma Lepri A1 Carla Macieira A1 Marco Matucci-Cerinic A1 Carlo Maurizio Montecucco A1 Maria Francisca Moraes-Fontes A1 Luc Mouthon A1 Sabrina Paolino A1 Veronique Ramoni A1 Chiara Tani A1 Sander W Tas A1 Angela Tincani A1 Ronald Van Vollenhoven A1 Margherita Zen A1 Joao Fonseca A1 Stefano Bombardieri A1 João Eurico Fonseca A1 Matthias Schneider A1 Vanessa Smith A1 Maurizio Cutolo A1 Marta Mosca A1 Lorenzo Beretta YR 2019 UL http://rmdopen.bmj.com/content/4/Suppl_1/e000786.abstract AB The term ‘undifferentiated connective tissue disease’ (UCTD) is generally used to describe clinical entities characterised by clinical and serological manifestations of systemic autoimmune diseases but not fulfilling the criteria for defined connective tissue diseases (CTDs). In this narrative review, we summarise the results of a systematic literature research, which was performed as part of the ERN ReCONNET project, aimed at evaluating existing clinical practice guidelines (CPGs) or recommendations.No specific CPG on UCTD were found, potential areas of intervention are absence of a consensus definition of UCTD, need for specific monitoring and therapeutic protocols, stratification of UCTD based on the risk of developing a defined CTD and preventive measure for the future development of a more severe condition.Patients feel uncertainty regarding the name of the disease and feel the need of a better education and understanding of these conditions and its possible changes over time.