PT - JOURNAL ARTICLE AU - Emma Swärdh AU - Christina Opava AU - Nina Brodin TI - Physical activity in patients with rheumatoid arthritis - an agile lifelong behaviour: a qualitative meta-synthesis AID - 10.1136/rmdopen-2021-001635 DP - 2021 May 01 TA - RMD Open PG - e001635 VI - 7 IP - 2 4099 - http://rmdopen.bmj.com/content/7/2/e001635.short 4100 - http://rmdopen.bmj.com/content/7/2/e001635.full SO - RMD Open2021 May 01; 7 AB - Background Physical activity (PA) in rheumatoid arthritis (RA) is considered a cornerstone in the treatment. To highlight aspects involved in supporting a positive PA behaviour, it is important to understand the patients’ perceptions of the phenomenon.Objective The aim of this qualitative meta-synthesis was to explore and synthesise patient perceptions of PA in RA.Methods A purposeful search was conducted across three online databases (PubMed, CINAHL and Web of Science). The methodological quality of the included studies was appraised, and data were extracted and analysed using an interpretive inductive thematic synthesis.Results Fifteen studies met the inclusion criteria and were included. PA was identified as an agile lifelong behaviour, with one main theme: The disease as a persistent catalyst for or against PA illustrating how the constant presence of the disease itself underlies the entire process of a life with or without regular PA. Seven subthemes: ‘considering aggravated symptoms’, ‘acknowledging the impact on health’, ‘becoming empowered and taking action’, ‘keeping informed to increase awareness’, ‘creating body awareness’, ‘dealing with social support’ and ‘feeling satisfied with circumstances and achievements’ were interpreted as facilitators and/or challenges.Conclusion This synthesis has identified PA as an agile lifelong behaviour in which the disease pervades all aspects of an individuals’ perception of PA. Placed in a theoretical context, our findings outline a model for tailoring PA support to the drivers and determinants of a certain individual, which will improve clinical practice for the benefit of both health professionals and patients with RA.Data are available on reasonable request.