RT Journal Article
SR Electronic
T1 Diabetes mellitus and cardiovascular risk management in patients with rheumatoid arthritis: an international audit
JF RMD Open
JO RMD Open
FD EULAR
SP e001724
DO 10.1136/rmdopen-2021-001724
VO 7
IS 2
A1 Anne Grete Semb
A1 Silvia Rollefstad
A1 Eirik Ikdahl
A1 Grunde Wibetoe
A1 Joseph Sexton
A1 Cindy Crowson
A1 Piet van Riel
A1 George Kitas
A1 Ian Graham
A1 Solbritt Rantapää-Dahlqvist
A1 George Athanasios Karpouzas
A1 Elena Myasoedova
A1 Miguel A Gonzalez-Gay
A1 Petros P Sfikakis
A1 Maria G Tektonidou
A1 Argyro Lazarini
A1 Dimitrios Vassilopoulos
A1 Bindee Kuriya
A1 Carol Hitchon
A1 Maria Simona Stoenoiu
A1 Patrick Durez
A1 Virginia Pascual-Ramos
A1 Dionicio Angel Galarza-Delgado
A1 Pompilio Faggiano
A1 Durga Prasanna Misra
A1 Andrew A Borg
A1 Rong Mu
A1 Erkin M Mirrakhimov
A1 Diane Gheta
A1 Karen Douglas
A1 Vikas Agarwal
A1 Svetlana Myasoedova
A1 Lev Krougly
A1 Tatiana Valentinovna Popkova
A1 Alena Tuchyňová
A1 Michal Tomcik
A1 Michal Vrablik
A1 Jiri Lastuvka
A1 Pavel Horak
A1 Helena Kaspar Medkova
A1 Anne M Kerola
A1 ,
YR 2021
UL http://rmdopen.bmj.com/content/7/2/e001724.abstract
AB Aim The objective was to examine the prevalence of atherosclerotic cardiovascular disease (ASCVD) and its risk factors among patients with RA with diabetes mellitus (RA-DM) and patients with RA without diabetes mellitus (RAwoDM), and to evaluate lipid and blood pressure (BP) goal attainment in RA-DM and RAwoDM in primary and secondary prevention.Methods The cohort was derived from the Survey of Cardiovascular Disease Risk Factors in Patients with Rheumatoid Arthritis from 53 centres/19 countries/3 continents during 2014–2019. We evaluated the prevalence of cardiovascular disease (CVD) among RA-DM and RAwoDM. The study population was divided into those with and without ASCVD, and within these groups we compared risk factors and CVD preventive treatment between RA-DM and RAwoDM.Results The study population comprised of 10 543 patients with RA, of whom 1381 (13%) had DM. ASCVD was present in 26.7% in RA-DM compared with 11.6% RAwoDM (p<0.001). The proportion of patients with a diagnosis of hypertension, hyperlipidaemia and use of lipid-lowering or antihypertensive agents was higher among RA-DM than RAwoDM (p<0.001 for all). The majority of patients with ASCVD did not reach the lipid goal of low-density lipoprotein cholesterol <1.8 mmol/L. The lipid goal attainment was statistically and clinically significantly higher in RA-DM compared with RAwoDM both for patients with and without ASCVD. The systolic BP target of <140 mm Hg was reached by the majority of patients, and there were no statistically nor clinically significant differences in attainment of BP targets between RA-DM and RAwoDM.Conclusion CVD preventive medication use and prevalence of ASCVD were higher in RA-DM than in RAwoDM, and lipid goals were also more frequently obtained in RA-DM. Lessons may be learnt from CVD prevention programmes in DM to clinically benefit patients with RA .No data are available. All data relevant to the study are included in the article or uploaded as supplementary information. The data were pseudonymised by each centre before transferred to the data handling centre at Diakonhjemmet hospital, where it is stored on a central server. The data handling manager is Joe Sexton (joesexton0@gmail.com) and the data centre leader is Anne Grete Semb (a-semb@diakonsyk.no).