RT Journal Article
SR Electronic
T1 Diabetes mellitus and cardiovascular risk management in patients with rheumatoid arthritis: an international audit
JF RMD Open
JO RMD Open
FD EULAR
SP e001724
DO 10.1136/rmdopen-2021-001724
VO 7
IS 2
A1 Semb, Anne Grete
A1 Rollefstad, Silvia
A1 Ikdahl, Eirik
A1 Wibetoe, Grunde
A1 Sexton, Joseph
A1 Crowson, Cindy
A1 van Riel, Piet
A1 Kitas, George
A1 Graham, Ian
A1 Rantapää-Dahlqvist, Solbritt
A1 Karpouzas, George Athanasios
A1 Myasoedova, Elena
A1 Gonzalez-Gay, Miguel A
A1 Sfikakis, Petros P
A1 Tektonidou, Maria G
A1 Lazarini, Argyro
A1 Vassilopoulos, Dimitrios
A1 Kuriya, Bindee
A1 Hitchon, Carol
A1 Stoenoiu, Maria Simona
A1 Durez, Patrick
A1 Pascual-Ramos, Virginia
A1 Galarza-Delgado, Dionicio Angel
A1 Faggiano, Pompilio
A1 Misra, Durga Prasanna
A1 Borg, Andrew A
A1 Mu, Rong
A1 Mirrakhimov, Erkin M
A1 Gheta, Diane
A1 Douglas, Karen
A1 Agarwal, Vikas
A1 Myasoedova, Svetlana
A1 Krougly, Lev
A1 Valentinovna Popkova, Tatiana
A1 Tuchyňová, Alena
A1 Tomcik, Michal
A1 Vrablik, Michal
A1 Lastuvka, Jiri
A1 Horak, Pavel
A1 Medkova, Helena Kaspar
A1 Kerola, Anne M
A1 
YR 2021
UL http://rmdopen.bmj.com/content/7/2/e001724.abstract
AB Aim The objective was to examine the prevalence of atherosclerotic cardiovascular disease (ASCVD) and its risk factors among patients with RA with diabetes mellitus (RA-DM) and patients with RA without diabetes mellitus (RAwoDM), and to evaluate lipid and blood pressure (BP) goal attainment in RA-DM and RAwoDM in primary and secondary prevention.Methods The cohort was derived from the Survey of Cardiovascular Disease Risk Factors in Patients with Rheumatoid Arthritis from 53 centres/19 countries/3 continents during 2014–2019. We evaluated the prevalence of cardiovascular disease (CVD) among RA-DM and RAwoDM. The study population was divided into those with and without ASCVD, and within these groups we compared risk factors and CVD preventive treatment between RA-DM and RAwoDM.Results The study population comprised of 10 543 patients with RA, of whom 1381 (13%) had DM. ASCVD was present in 26.7% in RA-DM compared with 11.6% RAwoDM (p<0.001). The proportion of patients with a diagnosis of hypertension, hyperlipidaemia and use of lipid-lowering or antihypertensive agents was higher among RA-DM than RAwoDM (p<0.001 for all). The majority of patients with ASCVD did not reach the lipid goal of low-density lipoprotein cholesterol <1.8 mmol/L. The lipid goal attainment was statistically and clinically significantly higher in RA-DM compared with RAwoDM both for patients with and without ASCVD. The systolic BP target of <140 mm Hg was reached by the majority of patients, and there were no statistically nor clinically significant differences in attainment of BP targets between RA-DM and RAwoDM.Conclusion CVD preventive medication use and prevalence of ASCVD were higher in RA-DM than in RAwoDM, and lipid goals were also more frequently obtained in RA-DM. Lessons may be learnt from CVD prevention programmes in DM to clinically benefit patients with RA .No data are available. All data relevant to the study are included in the article or uploaded as supplementary information. The data were pseudonymised by each centre before transferred to the data handling centre at Diakonhjemmet hospital, where it is stored on a central server. The data handling manager is Joe Sexton (joesexton0@gmail.com) and the data centre leader is Anne Grete Semb (a-semb@diakonsyk.no).