RT Journal Article
SR Electronic
T1 Fibromyalgia: a new facet of the post-COVID-19 syndrome spectrum? Results from a web-based survey
JF RMD Open
JO RMD Open
FD EULAR
SP e001735
DO 10.1136/rmdopen-2021-001735
VO 7
IS 3
A1 Francesco Ursini
A1 Jacopo Ciaffi
A1 Luana Mancarella
A1 Lucia Lisi
A1 Veronica Brusi
A1 Carlotta Cavallari
A1 Martina D’Onghia
A1 Anna Mari
A1 Elena Borlandelli
A1 Jacopo Faranda Cordella
A1 Micaela La Regina
A1 Pasquale Viola
A1 Piero Ruscitti
A1 Marco Miceli
A1 Roberto De Giorgio
A1 Nicola Baldini
A1 Claudio Borghi
A1 Alessandro Gasbarrini
A1 Annamaria Iagnocco
A1 Roberto Giacomelli
A1 Cesare Faldini
A1 Maria Paola Landini
A1 Riccardo Meliconi
YR 2021
UL http://rmdopen.bmj.com/content/7/3/e001735.abstract
AB Objective Postacute COVID-19 syndrome (PACS) is an emerging entity characterised by a large array of manifestations, including musculoskeletal complaints, fatigue and cognitive or sleep disturbances. Since similar symptoms are present also in patients with fibromyalgia (FM), we decided to perform a web-based cross-sectional survey aimed at investigating the prevalence and predictors of FM in patients who recovered from COVID-19.Methods Data were anonymously collected between 5 and 18 April 2021. The collection form consisted of 28 questions gathering demographic information, features and duration of acute COVID-19, comorbid diseases, and other individual’s attributes such as height and weight. The American College of Rheumatology (ACR) Survey Criteria and the Italian version of the Fibromyalgia Impact Questionnaire completed the survey.Results A final sample of 616 individuals (77.4% women) filled the form 6±3 months after the COVID-19 diagnosis. Of these, 189 (30.7%) satisfied the ACR survey criteria for FM (56.6% women). A multivariate logistic regression model including demographic and clinical factors showed that male gender (OR: 9.95, 95% CI 6.02 to 16.43, p<0.0001) and obesity (OR: 41.20, 95% CI 18.00 to 98.88, p<0.0001) were the strongest predictors of being classified as having post-COVID-19 FM. Hospital admission rate was significantly higher in men (15.8% vs 9.2%, p=0.001) and obese (19.2 vs 10.8%, p=0.016) respondents.Conclusion Our data suggest that clinical features of FM are common in patients who recovered from COVID-19 and that obesity and male gender affect the risk of developing post-COVID-19 FM.Data are available upon reasonable request. Data are available upon request from the corresponding author.