RT Journal Article
SR Electronic
T1 Possibilities for personalised medicine in rheumatoid arthritis: hype or hope
JF RMD Open
JO RMD Open
FD EULAR
SP e001653
DO 10.1136/rmdopen-2021-001653
VO 7
IS 3
A1 Judith Heutz
A1 Pascal Hendrik Pieter de Jong
YR 2021
UL http://rmdopen.bmj.com/content/7/3/e001653.abstract
AB Knowledge of pathophysiology of rheumatoid arthritis (RA) has improved over the past decades, which resulted in new treatment options and strategies that led to better clinical outcomes. At the same time, we have come to understand that RA is a heterogeneous disease on a clinical as well as a pathophysiological level. Despite this heterogeneity, current management recommendations still adopt a ‘one-size-fits-all’ treatment approach, where ideally individualised treatment, or personalised medicine, is preferred. The first step towards personalised medicine in RA would be to designate different treatment strategies to distinct clinical or molecular phenotypes of patients. This viewpoint discusses current evidence and elaborates on future possibilities for personalised medicine in RA.