Table 1

Composite indices assessed in PsA randomised controlled trials 2010–2015

Patient reported domainsPhysician reported domains
Composite indexNumber (%) RCTs assessing each index
RCT RefPainPsA globalJointSkinPhysical functionDisabilitySpineQuality of lifeGeneral healthJointsPsA globalDactylitisEnthesitisSkinESR/CRP
ACR response18 (82)(23–26, 29–34, 38–40, 43–47)XXXXXX
DAS-2816 (73)(23, 24, 27, 28, 30, 31, 33, 36, 38, 40, 42–47)XXX
8 (36)(25, 32, 33, 38, 39, 45–47)XXX
EULAR response6 (27)(27, 30, 33, 38, 46, 47)XXX
MDA4 (18)(15, 30, 31, 34, 39)XXXXXX
CDAI2 (9)(40, 45)XXX
PASDAS2 (9)(15, 31, 39)XXXXXXX
CPDAI2 (9)(15, 31, 39)XXXXXXXX
DAPSA2 (9)(15, 31) (11, 25)XXXXX
AMDF2 (9)(15, 31) (11, 25)XXXXXXX
GRACE1 (5)(15, 31)XXXXXXX
  • Patient Reported Domains: Joint and Skin is 100 mm visual analogue scale, Physical Function is Short Form-36 Physical Component Score, Disability is Health Assessment Questionnaire, Spine is Bath Ankylosing Spondylitis Disease Activity Index, Quality of Life is Psoriatic Arthritis Quality of Life Index in GRACE/AMDF; and Dermatology Life Quality Index and Ankylosing Spondylitis Quality of Life Index (both included) in CPDAI. Ref 15 is secondary data analysis of RCT ref 31 and ref 11 is secondary data analysis of RCT ref 25.

  • ACR, American College of Rheumatology; AMDF, Arithmetic Mean of the Desirability Function; CDAI, Clinical Disease Activity Index; CPDAI, Composite Psoriatic Disease Activity Index; CRP, C reactive protein; DAPSA, Disease Activity Index for Psoriatic Arthritis; DAS, Disease Activity Score; ESR, erythrocyte sedimentation rate; EULAR, European League Against Rheumatism; GRACE, Group for Research and Assessment of Psoriasis and Psoriatic Arthritis Composite Exercise; MDA, Minimal Disease Activity; PASDAS, Psoriatic Arthritis Disease Activity Score; PsARC, Psoriatic Arthritis Response Criteria; RCTs, randomised controlled trials.