Patient distribution according to methods of assessment and diagnosis
| Baseline characteristics | All patients Mean (±SD) (N=26) | RA (N=12) | PsA (N=2) | DM (RA) overlap (1), SLE (1), Sicca syndrome (2) (N=4) | FM (1), idiopathic gout (1), joint pain (2) (N=4) | JIA (1), polyarthritis (1), UIA (2) (N=4) |
|---|---|---|---|---|---|---|
| Gender (female): N (%) | 18 (69.2) | 9 (75) | 1 (50) | 3 (75) | 3 (75) | 2 (50) |
| Age (years) | 51.5 (±17.5) | 54.3 (±16.3) | 47 (±1) | 45.3 (±12.7) | 44 (±15) | 58.8 (±23.5) |
| Symptom duration (months) | 22.3 (±26.5) | 20.3 (±25.5) | 43.5 (±40.5) | 23.3 (±11.7) | 31.3 (±33.4) | 7.5 (±3.2) |
| Anti-CCP status: | ||||||
| Positive: N (%) | 15 (57.7) | 9 (75) | 0 (0) | 3 (75) | 2 (50) | 1 (25) |
| Negative: N (%) | 11 (42.3) | 3 (25) | 2 (100) | 1 (25) | 2 (50) | 3 (75) |
| RF status: | ||||||
| Positive: N (%) | 9 (34.6) | 5 (41.7) | 1 (50) | 3 (75) | 0 (0) | 1 (25) |
| Negative: N (%) | 17 (65.4) | 7 (58.3) | 1 (50) | 1 (25) | 4 (100) | 3 (75) |
| ESR levels (mm/h) | 22.3 (±18.6) | 28.3 (±21.1) | 6 (±2) | 35.3 (±10.9) | 6.8 (±2.2) | 15.3 (±9.0) |
| CRP levels (mg/L) | 11.9 (±23.2) | 20.3 (±31.5) | 1.8 (±1.2) | 10.3 (±8.6) | 1.5 (±0.9) | 3.5 (±1.8) |
| Smoking: previous and current status: N (%) | 16 (61.5) | 7 (58.3) | 1 (50) | 3 (75) | 2 (50) | 1 (25) |
| X-rays (bone erosions): N (%) | 7 (29.9) | 4 (33.3) | 1 (50) | 0 (0) | 1 (25) | 1 (25) |
| Clinical assessment | ||||||
| Hand and/or wrist inflammation: N (%) | 18 (69.2) | 10 (83.3) | 2 (100) | 2 (50) | 2 (50) | 2 (50) |
| Hand and wrist Joints swollen | 5.5 (±7.5) | 9.7 (±9.1) | 2 (±1) | 1.8 (±2) | 1.3 (±1.3) | 2.8 (±2.8) |
| MSUS | ||||||
| Hand and/or wrist inflammation: N (%) | 23 (88.5) | 12 (100) | 2 (100) | 3 (75) | 3 (75) | 3 (75) |
| MSUS synovitis Joint count | 9.3 (±9.7) | 12.2 (±9.8) | 14.5 (±11.5) | 7.8 (±10.6) | 3 (±2.5) | 6 (±6.4) |
| Fluorescence optical imaging | ||||||
| Hand and/or wrist inflammation: N (%) | 22 (84.6) | 11 (91.7) | 2 (100) | 3 (75) | 3 (75) | 3 (75) |
| FOI synovitis Joint count | 8.8 (±8.8) | 11.8 (±10.0) | 16 (±6) | 6 (±7.6) | 3 (±2.5) | 4.8 (±4.0) |
Anti-CCP, anti-cyclic citrullinated peptide; CRP, C reactive protein; DM, dermatomyositis; ESR, erythrocyte sedimentation rate; FM, fibromyalgia; FOI, fluorescence optical imaging; JIA, juvenile idiopathic arthritis; MSUS, musculoskeletal ultrasound; PsA, psoriatic arthritis; RA, rheumatoid arthritis; RF, rheumatoid factor; SLE, systemic lupus erythaematosus; SS, Sjögrens Syndrome; UIA, undifferentiated inflammatory arthritis.