TableĀ 2

Some strengths and weaknesses of PROs

The pathway in RAThe strong points of PROsThe weak points of PROs
InflammationPROs only indirectly reflect inflammation
SymptomsPROs reflect the patient's perspective and symptomsDealing with discordance between the physician and the patient, in treatment choices
Information that is distinct from physician-derived measuresRedundancy of information
Good psychometric propertiesDevelopment and validation of PROs not always optimal
Sensitivity to change
DamagePredictive validity for structural damage is limited or unknown
  • PROs, patient-reported outcomes; RA, rheumatoid arthritis.