Patients | Absolute blood neutrophil count (mm3) | Number of cycles | Diagnosis | Concomitant IS | Infectious site | Ab +G-CSF | Favourable outcome |
---|---|---|---|---|---|---|---|
1 | 90 | 2 | SLE | Cyclophosphamide | Febrile agranulocytosis | Yes | Yes |
2 | 430 | 1 | SLE | None | Broncho-pulmonary | Yes | Yes |
3 | <500 | 4 | GPA | None | Febrile agranulocytosis | Yes | Yes |
4 | <500 | 1 | SLE | Cyclophosphamide | Pyelonephritis | Yes | Yes |
5 | 650 | 2 | RA | Prednisolone 5 mg/day Methotrexate 7.5 mg/week | Pyelonephritis | Yes | Yes |
Ab, antibiotics; G-CSF, granulocyte colony-stimulating factor; GPA, granulomatosis with polyangiitis; IS, immunosuppressant; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus.