Generalised ordered logistic regression analysis of the association between rheumatoid arthritis and pain score site
| Pain vs no pain | >1 vs ≤1 site | ≥4 vs <4 sites | Whole body vs ≤7 sites | |
|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Univariate | ||||
| No RA | 1.00 | 1.00 | 1.00 | 1.00 |
| All self-reported RA | 2.86*** (2.68 to 3.06) | 3.43*** (3.25 to 3.62) | 5.42*** (5.12 to 5.75) | 9.08*** (8.38 to 9.84) |
| No RA | 1.00 | 1.00 | 1.00 | 1.00 |
| Treated RA | 2.74*** (2.50 to 3.01) | 3.47*** (3.21 to 3.74) | 5.36*** (5.30 to 6.21) | 12.44*** (11.26 to 13.75) |
| No RA | 1.00 | 1.00 | 1.00 | 1.00 |
| Steroids only | 6.70*** (3.04 to 14.78) | 6.70*** (3.04 to 14.78) | 6.70*** (3.04 to 14.78) | 6.70*** (3.04 to 14.78) |
| 1 synthetic DMARD | 2.52*** (2.24 to 2.83) | 3.16*** (2.87 to 3.49) | 5.35*** (4.82 to 5.93) | 11.34*** (9.93 to 12.94) |
| >1 synthetic DMARD | 3.15*** (2.67 to 3.71) | 3.92*** (3.44 to 4.47) | 6.13*** (5.37 to 7.00) | 14.03*** (11.96 to 16.45) |
| Biologic DMARD | 2.89*** (1.82 to 4.60) | 4.20*** (2.86 to 6.16) | 8.42*** (5.83 to 12.14) | 15.16*** (9.69 to 23.74) |
| Multivariate | ||||
| No RA | 1.00 | 1.00 | 1.00 | 1.00 |
| All self-reported RA | 2.58*** (2.41 to 2.76) | 3.04*** (2.87 to 3.22) | 4.43*** (4.17 to 4.71) | 6.99*** (6.43 to 7.61) |
| No RA | 1.00 | 1.00 | 1.00 | 1.00 |
| Treated RA | 2.52*** (2.30 to 2.78) | 3.12*** (2.288 to 3.38) | 4.86*** (4.46 to 5.28) | 10.17*** (9.15 to 11.29) |
| No RA | 1.00 | 1.00 | 1.00 | 1.00 |
| Steroids only | 5.32*** (2.36 to 11.96) | 5.32*** (2.36 to 11.96) | 5.32*** (2.36 to 11.96) | 5.32*** (2.36 to 11.96) |
| 1 synthetic DMARD | 2.34*** (2.08 to 2.64) | 2.86*** (2.59 to 3.17) | 4.61*** (4.14 to 5.15) | 9.42*** (8.21 to 10.81) |
| >1 synthetic DMARD | 2.84*** (2.41 to 3.36) | 3.49*** (3.05 to 3.99) | 5.03*** (4.38 to 5.78) | 11.19*** (9.45 to 13.25) |
| Biologic DMARD | 2.72*** (1.71 to 4.34) | 3.97*** (2.68 to 5.88) | 7.34*** (5.02 to 10.72) | 12.90*** (8.16 to 20.37) |
Multivariate: adjusted for age, sex, ethnicity, deprivation quintile, smoking, body mass index and alcohol intake.
**p<0.01; ***p<0.001.
DMARD, disease-modifying antirheumatic drug; RA, rheumatoid arthritis.