axSpA N=168 | no-axSpA N=260 | |||||
---|---|---|---|---|---|---|
Total group | BMI ≤24.9 N=117 | BMI ≥25 N=51 | Total group | BMI ≤24.9 N=141 | BMI ≥25 N=119 | |
Age, mean (SD), years | 30.2 (8.2) | 29.5 (8.4) | 31.9 (7.8) | 31.7 (8.4) | 29.3 (8.2)§ | 34.6 (7.7)§ |
Gender (male), n (%) | 81 (48.2)§ | 55 (47) | 26 (51) | 77 (29.6)§ | 39 (27.7) | 38 (31.9) |
HLA-B27+, n (%) | 156 (92.9)§ | 112 (95.7)ŧ | 44 (86.3)ŧ | 24 (9.3)§ | 16 (11.4) | 8 (6.8) |
BMI, mean (SD) | 24.5 (5.6) | 21.8 (2.0)§ | 30.6 (6.3)§ | 25.4 (5.1) | 21.9 (1.9)§ | 29.7 (4.4)§ |
Underweight (≤18.5), n (%) | 6 (3.6)ŧ | – | – | 8 (3.1)ŧ | – | – |
Normal (18.5–24.9), n (%) | 111 (66.1)ŧ | – | – | 133 (51.2)ŧ | – | – |
Overweight (25–29.9), n (%) | 31 (18.4)ŧ | – | – | 82 (31.5)ŧ | – | – |
Obese (≥30), n (%) | 20 (11.9)ŧ | – | – | 37 (14.2)ŧ | – | – |
CRP (mg/L) median (IQR), (range)* | 3 (3–7) (0–59) | 3 (2–5) (0.2–59)¤ | 4 (3–11) (0–41)¤ | 3 (3–6) (0–96) | 3 (3–5) (0–96)ŧ | 3 (3–6), (0.1–30)ŧ |
CRP ≥5, n (%) | 55 (32.7) | 32 (27.4)ŧ | 23 (45.1)ŧ | 89 (34.2) | 38 (27)¤ | 51 (42.9)¤ |
ESR (mm/h), median (IQR), (range) | 9 (5–15) (1–87) | 9 (5–15) (1–87) | 8.5 (4–18) (2–65) | 8 (2–14) (1–66) | 6 (2–10) (1–66)¤ | 9 (5–17) (1–50)¤ |
Physician global, mean (SD) | 5.2 (2.4) | 5.3 (2.5) | 5.0 (2.2) | 4.9 (2.3) | 4.9 (2.2) | 4.9 (2.4) |
Patient's global, mean (SD)* | 4.2 (2.6)§ | 4.2 (2.7) | 4.3 (2.5) | 5.2 (2.7)§ | 4.8 (2.7)ŧ | 5.6 (2.6)ŧ |
Total back pain, mean (SD)* | 4.7 (2.7)ŧ | 4.7 (2.6) | 4.8 (2.7) | 5.4 (2.7)ŧ | 5.1 (2.7) | 5.7 (2.7) |
Peripheral pain/swelling, mean (SD)* | 2.4 (2.8)¤ | 2.4 (2.7) | 2.6 (3.1) | 3.3 (3.0)¤ | 3.3 (3.1) | 3.3 (3.0) |
Duration of morning stiffness, mean (SD)* | 3.8 (2.8) | 3.7 (2.8) | 4.1 (2.9) | 4.3 (3.0) | 4.0 (2.9) | 4.6 (3.0) |
ASDAS, mean (SD) | 2.4 (0.9) | 2.3 (0.9)† | 2.6 (0.9)† | |||
BASDAI, mean (SD) | 3.9 (2.1) | 3.9 (2.1) | 4.2 (2.1) |
§p<0.001, ¤p<0.01,ŧp<0.05.
*Parameters of ASDAS.
†ASDAS p value=0.15.
ASDAS, Ankylosing Spondylitis Disease Activity Score; axSpA, axial spondyloarthritis; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BMI, body mass index; CRP, C reactive protein; ESR, erythrocyte sedimentation rate; HLA-B27, human leucocyte antigen B27.