Predictors of functional status, damage and inactive disease
| Variables | HAQ | JADI-A | JADI-E | Inactive disease | ||||
|---|---|---|---|---|---|---|---|---|
| β (95% CI) | p Value | β (95% CI) | p Value | β (95% CI) | p Value | OR (95% CI) | p Value | |
| Gender—female | −0.03 (−0.2 to 0.2) | 0.771 | 2.0 (−3.1 to 7.1) | 0.436 | −0.03 (−0,7 to 0.7) | 0.937 | 2.3 (0.2 to 31.3) | 0.528 |
| Age at the time of last visit (years) | 0.03 (0.0 to 0.04) | <0.0001* | 0.3 (0.1 to 0.5) | 0.004* | 0.02 (−0.0 to 0.1) | 0.102 | 0.9 (0.9 to 1) | 0.031* |
| Age at disease onset (years) | −0.02 (−0.04 to −0.0) | 0.021* | −0.9 (−1.4 to −0.3) | 0.003* | −0.1 (−0.8 to −0.0) | 0.008* | 1.4 (1.1 to 1.8) | 0.008* |
| Years of education | −0.02 (−0.1 to 0.0) | 0.055 | – | – | – | – | – | – |
| JIA ILAR category† | – | 0.4129 | – | 0.0349* | – | 0.5406 | – | 0.5123 |
| E. oligo | 0.04 (−0.3 to 0.4) | 0.798 | 4.5 (−3.2 to 12.2) | 0.246 | 0.5 (−0.6 to 1.5) | 0.372 | – | – |
| RF+ poly | 0.34 (0.0 to 0.7) | 0.036 | 16.2 (6.8 to 25.6) | 0.001* | −0.2 (−1.6 to 1.2) | 0.744 | 8.6 (0.3 to 221.7) | 0.194 |
| RF− poly | 0.10 (−0.2 to 0.4) | 0.501 | 6.2 (−0.8 to 13.2) | 0.081 | 0.8 (−0.2 to 1.7) | 0.124 | 5.1 (0.2 to 116.9) | 0.311 |
| SoJIA | 0.05 (−0.4 to 0.5) | 0.805 | 10.2 (1.0 to 19.3) | 0.029* | 0.3 (−1.0 to 1.7) | 0.635 | 4.2 (0.1 to 314.6) | 0.513 |
| ERA | 0.2 (−0.1 to 0.5) | 0.116 | 6.4 (−0.8 to 13.6) | 0.082 | 0.7 (−0.3 to 1.7) | 0.148 | 20.4 (0.5 to 853.8) | 0.114 |
| PsA | 0.1 (−0.5 to 0.6) | 0.844 | 0.2 (19.2 to 19.5) | 0.987 | 0.3 (−1.9 to 2.6) | 0.773 | – | – |
| Corticosteroids exposure (yes) | – | – | – | – | 1.1 (0.4 to 1.9) | 0.002* | – | – |
| ACPA positive | – | – | – | – | – | – | 0.1 (0.0 to 0.7) | 0.028* |
| RF positive | – | – | – | – | – | – | 12.9 (0.8 to 200.2) | 0.068 |
*Statistical significance.
†Persistent oligoarthritis used as comparator.
ACPA, anticitrullinated protein antibodies; E. oligo, extended oligoarthritis; ERA, enthesitis-related arthritis; HAQ, Health Assessment Questionnaire; ILAR, International League of Associations for Rheumatology; JADI, Juvenile Arthritis Damage Index; JIA, juvenile idiopathic arthritis; PsA, psoriatic arthritis; RF− poly, rheumatoid factor negative polyarthritis; RF, rheumatoid factor; RF+ poly, rheumatoid factor positive polyarthritis; SoJIA, systemic arthritis.