Demographic and traditional cardiovascular risk factors of patients with IIM
| Author, year | Group | n | F/M n | Age (years) | HT % | Smoke % | DB % | Obese, % | DL % | BMI kg/m2 | PG† | TC† | LDLc† | HDLc† | TG† |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coyle, 200940 | JDM | 17 | 14/3 | 4.6-16.4 | NA | 0 | 0 | 23.5 | 47.1 | 19.7 ∼ | 85 ∼ mg/dL | 165 ∼ mg/dL | 106∼ mg/dL | 39 ∼ mg/dL | 115 ∼ mg/dL |
| de Moraes, 201336 | DM | 84 105 | 67/17 83/22 | 41.5 42.0 | 47.6* 18.1 | 10.7 11.4 | 17.9* 1.0 | NA | 67.9* 49.5 | 27.5* 25.4 | 84*∼ 80 ∼ mg/dL | 180 ∼ 187 ∼ mg/dL | 88 ∼ 113 ∼ mg/dL | 49*∼ 54 ∼ mg/dL | 119*∼ 86 ∼ mg/dL |
| de Souza, 201437 | PM Controls | 35 70 | 27/8 54/16 | 49.7 48.7 | 45.7* 27.1 | 14.3 17.1 | 34.3* 4.3 | NA | 71.4* 51.4 | 27.5 26.0 | 91* ∼ 81 ∼ mg/dL | 196 ∼ 194 ∼ mg/dL | 111 ∼ 122 ∼ mg/dL | 57 55 mg/dL | 149* ∼ 99 mg/dL |
| Diederichsen 201422 | PM/DM Controls | 76 48 | 49/27 32/16 | 60.0 59.4 | 71* 42 | 25 17 | 13* 0 | 33* 10 | 88¶* 73 | 27.6 26.0 | 6.5 6.0 | 5.6 5.4 | 3.3 3.1 | 1.6 1.7 | 1.5* 1.1 |
| Eimer, 201141 | JDM Controls | 8 15 | 3/5 6/9 | 38 37 | NA | 25 0 | NA | NA | NA | 23 ∼ 24 ∼ | 94 ∼ 92 ∼ mg/dL | NA | 102* ∼ 113 ∼ mg/dL | 40* ∼ 53 ∼ mg/dL | 75 ∼ 66 ∼ mg/dL |
| Schwartz, 201442 | JDM Controls | 59 59 | 36/23 36/23 | 21.5 21.6 | 12* 0 | 23 17 | 0 0 | NA | NA | 22.3 22.5 | NA | 4.2* 4.6 | 2.3* 2.7 | 1.2* 1.5 | NA |
| Wang, 201338 | DM‡ Controls | 41 41 | 30/11 30/11 | 44.6 42.4 | 0 0 | NA | 0 0 | NA | 70.7¤ NA | NA | NA | 4.1 3.9 | 2.5 2.3 | 1.1* 1.3 | 2.2* 1.1 |
| Wang, 201357 | PM§ Controls | 71 71 | 56/15 56/15 | 46.9 46.2 | 0 0 | NA | 0 0 | NA | NA | NA | 5.0 5.1 | 4.8 4.7 | 2.2* 1.8 | 2.0* 2.4 | 1.7* 1.3 |
| Wang, 201439 | PM‡ Controls | 60 60 | 44/16 44/16 | 42.9 42.9 | 0 0 | 10 10 | 0 0 | NA | 47¤* 20 | 22.7 22.1 | NA | 4.1* 4.7 | 2.4* 2.7 | 0.9* 1.5 | 1.9* 1.3 |
| Wang, 201414 | DM§ Controls | 51 51 | 43/8 43/8 | 44.1 44.4 | 0 0 | NA | 0 0 | NA | NA | NA | 4.8 4.8 | 4.8 4.8 | 2.9 2.7 | 1.4 1.5 | 1.7* 1.4 |
*p<0.05; JDM: juvenile dermatomyositis;.
†Units are mmol/L unless otherwise indicated and values are mean unless marked with ∼=median.
‡Untreated patients without hypertension, diabetes and cardiovascular heart disease.
§Patients without hypertension, diabetes and cardiovascular heart disease.
¶Hypercholesterolemia. ¤hypertriglyceridemia.
BMI, body mass index; DL, dyslipidaemia; DM, diabetes mellitus; DM: dermatomyositis; F/M, female/male; HDLc, high-density lipoprotein cholesterol; HT, hypertension; IIM, idiopathic inflammatory myopathies; LDLc, low-density lipoprotein cholesterol; NA, not available; PG, plasma glucose; PM: polymyositis; TC, total cholesterol; TG, triglycerides.