Table 3

Effect of NSAIDs on spinal radiographic progression in patients with r-axSpA

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  • Bold=significant (p<0.05).

  • Sieper 2015: Diclofenac continuous (150 mg/day, at least 75 mg/day) versus on-demand (negative trial).

  • Kroon 2012: Celecoxib continuous (200 mg/day, increase to 400 mg/day was allowed) versus on-demand (positive trial).

  • CI, confidence interval; CRP, C reactive protein; mSASSS, modified Stoke Ankylosing Spondylitis Spinal Score; NR, not reported; NSAIDs, non-steroidal anti-inflammatory drugs; r-axSpA, radiographic axial spondyloarthritis; SD, standard deviation.