Baseline demographic, clinical and radiographic characteristics of patients for cross-sectional and longitudinal analyses
| Cross-sectional, n=869 | Longitudinal, n=307 | p Value | |
|---|---|---|---|
| Age (years), mean±SD | 64.0±7 | 63.8±7.1 | 0.56 |
| Sex | 0.94 | ||
| Women, n (%) | 622 (72) | 213 (69) | |
| Menopause | 489 (78) | 166 (54.1) | 0.50 |
| Men, n (%) | 247 (28) | 86 (28) | |
| BMI (kg/m2), mean±SD | 29.6±4.7 | 29.5±5 | 0.55 |
| BMI<30, n (%) | 502 (58) | 172(56) | |
| BMI≥30, n (%) | 366 (42) | 127 (41) | |
| Comorbidities, n (%) | |||
| Diabetes | 82 (9) | 30 (10) | 0.91 |
| Hypertension | 413 (48) | 135 (44) | 0.28 |
| Dyslipidaemia | 245 (28) | 89 (29) | 0.82 |
| Coronary heart disease | 81 (9) | 35 (11) | 0.32 |
| Stroke | 16 (2) | 7 (2) | 0.63 |
| Depression | 81 (9) | 30 (10) | 0.82 |
| Alcohol consumption, n (%) | |||
| No | 422 (49) | 135 (44) | |
| Previous use | 16 (2) | 6 (2) | |
| Yes | 431 (50) | 158 (51) | 0.57 |
| Tobacco use, n (%) | |||
| No | 567 (65) | 188 (61) | |
| Previous use | 222 (26) | 86 (28) | |
| Yes | 80 (9) | 25 (8) | 0.53 |
| Clinical variables | |||
| FIHOA | |||
| 0–30, median [Q1, Q3] | 2.0 [0.0–7.0] | 2.0 [0.0–7.0] | 0.90 |
| ≥5+pain, n (%) | 126 (26) | 45 (15) | 0.83 |
| AUSCAN, median [Q1, Q3] | |||
| Overall (0–300) | 77.3 [23.4–156] | 77.5 [18.7–158] | 0.90 |
| Pain (0–100) | 25 [5.6–54.6] | 26.4 [4.8–55.8] | 0.84 |
| Stiffness (0–100) | 20 [4–54] | 20 [4–56] | 0.81 |
| Function (0–100) | 25.9 [7.2–52.2] | 25.4 [5.9–53.9] | 0.76 |
| Radiographic variables | |||
| KL hand score (0–128), median [Q1, Q3] | 18 [12–27] | 17 [12–28] | 0.75 |
| Number of erosive joints (phase E or R, Verbruggen score), median [Q1, Q3] | 2 [1–4] | 1 [1–3] | 0.45 |
| KL knee grade 2, n (%) | 532 (61) | 194(63) | 0.47 |
| KL knee grade 3, n (%) | 336 (39) | 105 (24) | |
AUSCAN, AUStralian-CANadian; BMI, body mass index; FIHOA, Functional Index for Hand Osteoarthritis; KL, Kellgren-Lawrence; Q1, Q3, quartile 1, quartile 3.