Table 1

Response rates

ResponseWeekModified-release prednisoneImmediate-release prednisone
Per protocol population (N=26)Full analysis population (N=32)Per protocol population (N=22)Full analysis population (N=30)
Complete response* (n (%))13 (11.5)5 (15.6)4 (18.2)4 (13.3)
27 (26.9)9 (28.1)7 (31.8)7 (23.3)
414 (53.8)17 (53.1)9 (40.9)10 (33.3)
Partial response† (n (%))18 (30.8)8 (25.0)1 (4.5)1 (3.3)
211 (42.3)13 (40.6)2 (9.1)2 (6.7)
46 (23.1)8 (25.0)3 (13.6)4 (13.3)
  • *Complete response was defined as all three of the following: (1) ≥70% improvement from baseline in the polymyalgia rheumatica visual analogue scale, (2) ≥70% reduction in the duration of morning stiffness and (3) ≥70% reduction in the C reactive protein (CRP) value (or CRP <2× upper limit of normal).

  • †Partial response was defined as two of the above three criteria being met.