VEGF concentration predicts biopsy positivity but is not useful to identify other diagnostic subgroups. Performance of VEGF expressed as sensitivity and specificity based on data dichotomised by the cut-off of 713 pg/mL, subgrouped according to method of diagnosis
| Parameter | All patients | Clinically diagnosed GCA | Ultrasound-positive GCA | Biopsy-proven GCA |
|---|---|---|---|---|
| Sensitivity | 34% | 25% | 34% | 58% |
| Specificity | 85% | 85% | 85% | 85% |
GCA, giant cell arteritis; VEGF, vascular endothelial growth factor.