ACIP recommendation for categories of immunosuppression therapy dosing
| Immunosuppressive therapy | Definition of ‘high-level immunosuppression’ |
| Corticosteroids | ≥20 mg/day for ≥14 days |
| Azathioprine | >3.0 mg/kg/day |
| Methotrexate | >0.4 mg/kg/week |
| 6-Mercaptopurine | >1.5 mg/kg/day |
| TNF-α inhibitors | Any dose |
| Rituximab | Any dose |
ACIP, Advisory Committee on Immunization Practices; TNF-α, tumour necrosis factor alpha.