IJD (n=86) | RA (n=55) | AS (n=21) | PsA (n=10) | p Value† | |
Age, years | 60.8±8.5 | 62.2±8.6 | 58.8±8.3 | 57.2±7.6 | 0.11 |
Women, n (%) | 52 (60.5) | 40 (72.7) | 7 (33.3) | 5 (50.0) | 0.01 |
Disease duration (years), median (IQR) | 16 (8.0–25.0) | 16 (7.0–22.3) | 21 (9.5–28.0) | 11.5 (1.5–29.5) | 0.19 |
BMI, kg/m2 | 25.3±3.2 | 25.0±2.6 | 25.4±2.6 | 26.4±3.7 | 0.44 |
Waist circumference, cm | 91.4±11.1 | 90.4±8.6 | 91.6±8.6 | 96.8±11.3 | 0.24 |
Systolic BP, mm Hg | 144±19 | 144±20 | 145±13 | 145±25 | 0.94 |
Diastolic BP, mm Hg | 84±9 | 83±9 | 85±9 | 87±11 | 0.53 |
Hypertension, n (%) | 51 (59.3) | 32 (58.2) | 14 (66.7) | 4 (40.0) | 0.76 |
Diabetes mellitus, n (%) | 6 (7.0) | 4 (7.3) | 2 (9.5) | 0 (0.0) | 0.60 |
Smoking, n (%) | 16 (18.6) | 11 (20.0) | 3 (14.3) | 2 (20.0) | 0.80 |
Family history of cardiovascular disease, n (%) | 12 (14.5) | 8 (14.5) | 1 (4.8) | 3 (30.0) | 0.57 |
Previous cardiovascular disease, n (%) | 9 (10.5) | 6 (10.9) | 3 (14.3) | 0 (0.0) | 0.47 |
Angina pectoris, n (%) | 18 (20.9) | 12 (28.6) | 6 (28.6) | 0 (0.0) | 0.33 |
Hyperlipidaemia, n (%) | 55 (64.0) | 33 (60.0) | 15 (71.4) | 7 (70.0) | 0.37 |
Lipids | |||||
Total cholesterol, mmol/L | 6.4±1.1 | 6.4±1.2 | 6.3±0.9 | 6.5±1.1 | 0.88 |
HDL cholesterol, mmol/L | 1.7±0.5 | 1.8±0.5 | 1.5±0.5 | 1.6±0.5 | 0.07 |
LDL cholesterol, mmol/L | 4.1±1.0 | 4.0±1.1 | 4.1±0.9 | 4.2±1.0 | 0.80 |
Triglycerides (mmol/L), median (IQR) | 1.2 (0.9–1.8) | 1.1 (0.9–1.6) | 1.6 (1.1–2.1) | 1.1 (0.7–2.9) | 0.23 |
Medications | |||||
Synthetic DMARDs, n (%) | 48 (63.2) | 34 (68.0) | 6 (31.6) | 9 (90.0) | 0.95 |
Biologic DMARDs, n (%) | 26 (34.2) | 16 (32.0) | 6 (31.6) | 5 (50.0) | 0.38 |
Inflammatory markers | |||||
ESR (mm/hour) | 14.4±9.3 | 15.3±9.6 | 12.1±9.8 | 13.9±6.0 | 0.42 |
CRP (mg/L), median (IQR) | 2.0 (1.0–4.0) | 3.0 (1.0–4.0) | 1.0 (1.0–5.0) | 2.5 (1.8–6.5) | 0.39 |
Hypertension, ≥140 mm Hg systolic, hyperlipidaemia: total cholesterol ≥6.0 mmol/L.
*Values expressed as mean±SD, unless indicated otherwise.
†Data compared by analysis of variance.
AS, ankylosing spondylitis; BMI, body mass index; BP, blood pressure; CRP, C-reactive protein; DMARDs, disease-modifying antirheumatic drugs; ESR, erythrocyte sedimentation rate; HDL, high-density lipoprotein; IJD, inflammatory joint disease; LDL, low-density lipoprotein; PsA, psoriatic arthritis; RA, rheumatoid arthritis.