Table 2

ROC area under the curve (AUC) analyses for hip and major osteoporotic fractures

	Hip fractures			Major osteoporotic fractures
	AUC	95% CI	p Value	AUC	95% CI	p Value
Women
BMD femoral neck alone	0.68	0.66 to 0.71	<0.009	0.66	0.63 to 0.68	<0.001
FRAX® without BMD	0.72† ns	0.69 to 0.74	<0.001	0.75†***	0.73 to 0.77	<0.001
FRAX® with BMD	0.75†‡** ns	0.62 to 0.87	<0.001	0.76†‡*** ns	0.74 to 0.78	<0.001
Men
BMD femoral neck alone	0.82	0.78 to 0.86	<0.004	0.80	0.76 to 0.84	<0.001
FRAX® without BMD	0.93†***	0.89 to 0.95	<0.001	0.81† ns	0.76 to 0.85	<0.001
FRAX® with BMD	0.90†‡***ns	0.86 to 0.93	<0.001	0.85†‡* ns	0.81 to 0.88	<0.001
Both
BMD femoral neck alone	0.72	0.61 to 0.83	<0.001	0.69	0.64 to 0.73	<0.001
FRAX® without BMD	0.78	0.69 to 0.86	<0.001	0.76†***	0.72 to 0.79	<0.001
FRAX® with BMD	0.79†‡*** ns	0.69 to 0.89	<0.001	0.78†‡*** ns	0.74 to 0.82	<0.001

*p<0.05.
**p<0.01.
***p<0.001.
†p Value versus same site/gender BMD alone.
‡p Value versus same site/gender FRAX® without BMD.
BMD, bone mineral density; ns, non-significant; ROC, receiver operating characteristic.