HRs for fracture based on individual FRAX® variables including femoral neck BMD
| Hip fractures | Major osteoporotic fractures | |||||
| HR | 95% CI | p Value | HR | 95% CI | p Value | |
| Sex (men vs women) | 0.58 | 0.21 to 1.59 | 0.287 | 1.32 | 0.80 to 2.20 | 0.276 |
| Age (years) | 1.12 | 1.07 to 1.18 | <0.001 | 1.03 | 1.01 to 1.05 | 0.006 |
| BMI (kg/m2) | 1.14 | 1.04 to 1.25 | 0.007 | 1.01 | 0.97 to 1.05 | 0.598 |
| Previous fracture(yes/no) | 1.23 | 0.48 to 3.11 | 0.669 | 2.47 | 1.72 to 3.55 | <0.001 |
| Parent hip fractures (yes/no) | 1.44 | 0.42 to 4.95 | 0.560 | 3.69 | 2.51 to 5.43 | <0.001 |
| Current smoking (yes/no) | 2.45 | 0.69 to 8.68 | 0.165 | 1.72 | 1.05 to 2.81 | 0.031 |
| Glucocorticoids (yes/no) | 2.62 | 0.92 to 7.49 | 0.072 | 2.80 | 1.78 to 4.41 | <0.001 |
| Rheumatoid arthritis (yes/no) | 1.68 | 0.42 to 6.69 | 0.461 | 1.36 | 0.74 to 2.48 | 0.318 |
| Secondary osteoporosis (yes/no) | 1.22 | 0.48 to 3.09 | 0.673 | 1.43 | 1.00 to 2.05 | 0.049 |
| Alcohol three or more units day (yes/no) | 1.14 | 0.32 to 4.11 | 0.842 | 1.30 | 0.78 to 2.17 | 0.323 |
| Femoral neck T score | 0.60 | 0.41 to 0.87 | 0.007 | 0.72 | 0.62 to 0.83 | <0.001 |
BMD, bone mineral density; BMI, body mass index.