Table 3

Hazard ratios of development of rheumatoid arthritis according to drug exposure

Crude HRAdjusted HR (95% CI)*Competitive risk adjusted HR (95% CI)*†
TamoxifenReferenceReferenceReference
Aromatase inhibitors1.67 (1.08 to 2.60)1.64 (1.04 to 2.58)1.62 (1.03 to 2.56)
 Anastrozole1.77 (1.10 to 2.85)1.73 (1.06 to 2.81)1.75 (1.07 to 2.86)
 Letrozole1.51 (0.89 to 2.56)1.49 (0.87 to 2.56)1.47 (0.86 to 2.51)
 Exemestane1.78 (0.76 to 4.17)1.75 (0.74 to 4.16)1.47 (0.63 to 3.43)
  • *Adjusted for age at the beginning of the exposure period, level of neoplasia.

  • †Competing risk survival model.