Table 1

Comparison of T2 frequency selective fat saturation (T2 fatsat) or STIR images versus Gd-chelate enhanced T1 fast spin echo sequences with frequency-selective fat saturation (T1 Gd)—although the underlying cause for the signal intensity differs, the sequences perform equally in depicting bone marrow oedema (BME)

ComparisonMR scanner (T)PatientsPatients, nJoint/boneBME featureCorrelation coefficient(P values)Accuracy/sensitivity
Schmid et al 9 STIR versus T1Gd1.0Various orthopaedic diagnoses (osteoarthritis, osteonecrosis, insufficiency fractures and the majority (n=32) were non-specific cases51Foot and ankleBME volume0.98(p<0.001)nd
Mayerhoever et   al 8 STIR versus T1Gd1.0 or 1.5Various orthopaedic diagnoses (bone bruises, osteoarthritis, osteonecrosis, stress fractures)30KneeBME volumeSignal contrast0.99(p<0.001)0.94(p<0.001)nd nd
Tamai et al 10 STIR versus T1Gd1.5Early RA51Wrists,MCPs,PIPsPresence of BMEndAccuracy 98%
Stomp et al 7 T2 fatsat, versus T1Gd1.5Early arthritisAdvanced RA17643Wrist,MCPsBME scores according to RAMRIS, evaluated by two readers0.99 and0.870.99 and0.94 *Sens>95%Sens>95%
  • * Sensitivity for the presence of BME (defined as BME score ≥1) with T2 sequence as reference.

  • MCP, metacarpophalangeal; nd,not determined; PIP, proximal interphalangeal; RA, rheumatoid arthritis; RAMRIS, RA MRI score; STIR, Short-TI Inversion Recovery.