Demographic and clinical characteristics of people with vs without incident AF
| Entire cohort | AF during the follow-up | ||
| No | Yes | ||
| Total, N | 1 647 812* | 1 486 722 | 161 090 |
| Age, mean (SD) | 75.1 (7.6) | 75.0 (7.6) | 76.7 (7.2) |
| Gender, N (%) | |||
| Male | 694 358 (42.1%) | 621 069 (41.8%) | 73 289 (45.5%) |
| Female | 953 454 (57.9%) | 865 653 (58.2%) | 87 801 (54.5%) |
| Race/Ethnicity, N (%) | |||
| White | 1 412 663 (85.7%) | 1 266 743 (85.2%) | 145 920 (90.6%) |
| Black | 139 503 (8.5%) | 130 466 (8.8%) | 9037 (5.6%) |
| Other/unknown | 95 646 (5.8%) | 89 513 (6.0%) | 6133 (3.8%) |
| Charlson-Romano comorbidity score | |||
| 0 | 895 277 (54.3%) | 831 644 (55.9%) | 63 633 (39.5%) |
| 1 | 165 719 (10.1%) | 145 893 (9.8%) | 19 826 (12.3%) |
| ≥2 | 586 816 (35.6%) | 509 185 (34.2%) | 77 631 (48.2%) |
| Charlson-Romano comorbidity score, mean (SD) | 1.5 (2.3) | 1.5 (2.3) | 2.0 (2.4) |
| Charlson-Romano comorbidities | |||
| Myocardial infarction | 59 767 (3.6%) | 50 493 (3.4%) | 9274 (5.8%) |
| Heart Failure | 166 340 (10.1%) | 139 115 (9.4%) | 27 225 (16.9%) |
| Peripheral vascular disease | 152 816 (9.3%) | 130 465 (8.8%) | 22 351 (13.9%) |
| Cerebrovascular disease | 151 250 (9.2%) | 130 151 (8.8%) | 21 099 (13.1%) |
| Dementia | 73 121 (4.4%) | 67 567 (4.5%) | 5554 (3.4%) |
| Chronic pulmonary disease | 246 373 (15.0%) | 213 089 (14.3%) | 33 284 (20.7%) |
| Connective tissue disease | 44 644 (2.7%) | 38 548 (2.6%) | 6096 (3.8%) |
| Peptic ulcer disease | 30 219 (1.8%) | 26 376 (1.8%) | 3843 (2.4%) |
| Mild liver disease | 7968 (0.48%) | 7124 (0.48%) | 844 (0.52%) |
| Diabetes | 295 939 (18.0%) | 257 467 (17.3%) | 38 472 (23.9%) |
| Diabetes with end organ damage | 86 605 (5.3%) | 74 589 (5.0%) | 12 016 (7.5%) |
| Hemiplegia | 12 910 (0.78%) | 11 478 (0.77%) | 1432 (0.89%) |
| Renal failure/disease | 53 318 (3.2%) | 45 554 (3.1%) | 7764 (4.8%) |
| Any tumour leukaemia lymphoma | 161 515 (9.8%) | 141 779 (9.5%) | 19 736 (12.3%) |
| Moderate or severe liver disease | 1876 (0.11%) | 1744 (0.12%) | 132 (0.08%) |
| Metastatic cancer | 17 006 (1.0%) | 15 674 (1.1%) | 1332 (0.83%) |
| AIDS | 536 (0.03%) | 487 (0.03%) | 49 (0.03%) |
| Hypertension | 772 911 (46.9%) | 672 974 (45.3%) | 99 937 (62.0%) |
| Hyperlipidaemia | 560 195 (34.0%) | 489 856 (32.9%) | 70 339 (43.7%) |
| Coronary artery disease | 266 116 (16.1%) | 223 011 (15.0%) | 43 105 (26.8%) |
* Met eligibility criteria and did not have AF in the baseline 365-day period.
AF, atrial fibrillation.