Table 1

Population characteristics

VariableTotal (n=121)
Age (years: mean and SD)58±14.9
Gender (male: n, %)51 (42)
Diagnosis (n, %)
 PM30 (25)
 DM41 (34)
 NAM5 (4)
 IBM1 (1)
 ASS37 (31)
 Overlap myositis7 (6)
  Sjogren’s syndrome1
  Sarcoidosis1
  Systemic sclerosis2
  Morphea1
  SLE1
  Mixed connective tissue disease1
Disease duration (months: median and IQR)65 (106)
Smoking (n, %)53 (44)
MSA (≥5 AU) (n/patients checked, %)
 Mi-2
 SRP7/92 (8)
 NXP-22/95 (2)
 MDA-58/92 (9)
 TIF-1γ5/92 (5)
 SAE-1/22/92 (2)
MAA (n/patients checked, %)
 SSA/Ro-52 (≥ 5 AU)3/92 (3)34/97 (35)
 Ro-60 (≥ 7 U/mL)4/25 (16)
 U1-RNP (≥ 5 U/mL)5/74 (7)
 PM/Scl (≥ 7 U/mL)1/82 (1)
Anti-ARS (≥5 AU) (n/patients checked, %)
 Jo-131/106 (29)
 PL-72/95 (2)
 PL-123/95 (3)
 EJ2/92 (2)
HMGCR (≥5 AU) (n/patients checked, %)4/79 (5)
  • anti-ARS, anti-aminoacyl-tRNA synthetase antibodies; ASS, antisynthetase syndrome; AU, antibody units; DM, dermatomyositis; IBM, inclusion body myositis; HMGCR, anti-HMG-CoA reductase antibodies; MAA, myositis-associated antibodies; MSA, myositis-specific antibodies; NAM, necrotising autoimmune myopathy; PM, polymyositis; SLE, systemic lupus erythematosus .