Variable | Total (n=121) |
Age (years: mean and SD) | 58±14.9 |
Gender (male: n, %) | 51 (42) |
Diagnosis (n, %) | |
PM | 30 (25) |
DM | 41 (34) |
NAM | 5 (4) |
IBM | 1 (1) |
ASS | 37 (31) |
Overlap myositis | 7 (6) |
Sjogren’s syndrome | 1 |
Sarcoidosis | 1 |
Systemic sclerosis | 2 |
Morphea | 1 |
SLE | 1 |
Mixed connective tissue disease | 1 |
Disease duration (months: median and IQR) | 65 (106) |
Smoking (n, %) | 53 (44) |
MSA (≥5 AU) (n/patients checked, %) | |
Mi-2 | |
SRP | 7/92 (8) |
NXP-2 | 2/95 (2) |
MDA-5 | 8/92 (9) |
TIF-1γ | 5/92 (5) |
SAE-1/2 | 2/92 (2) |
MAA (n/patients checked, %) | |
SSA/Ro-52 (≥ 5 AU) | 3/92 (3)34/97 (35) |
Ro-60 (≥ 7 U/mL) | 4/25 (16) |
U1-RNP (≥ 5 U/mL) | 5/74 (7) |
PM/Scl (≥ 7 U/mL) | 1/82 (1) |
Anti-ARS (≥5 AU) (n/patients checked, %) | |
Jo-1 | 31/106 (29) |
PL-7 | 2/95 (2) |
PL-12 | 3/95 (3) |
EJ | 2/92 (2) |
HMGCR (≥5 AU) (n/patients checked, %) | 4/79 (5) |
anti-ARS, anti-aminoacyl-tRNA synthetase antibodies; ASS, antisynthetase syndrome; AU, antibody units; DM, dermatomyositis; IBM, inclusion body myositis; HMGCR, anti-HMG-CoA reductase antibodies; MAA, myositis-associated antibodies; MSA, myositis-specific antibodies; NAM, necrotising autoimmune myopathy; PM, polymyositis; SLE, systemic lupus erythematosus .