Characteristics of patients positive to RF and/or ACPA
| Patient | Age (years) | Gender | Diagnosis | RF (<40 IU/mL) | ACPA (<7 U/mL) | Antibody | Arthralgia | Arthritis | ILD | Smoking | Radiography |
| 1 | 69* | Female | ASS (PM) | 172 – 250 - 307 | 7.4 | Jo-1 (51 U/mL) | Yes | Yes | Yes | Previous | 2006 F: no erosions. |
| 2 | 43 | Female | DM | 162 | >340 | ANF (1/320) | Yes | No | No | Never | / |
| 3 | 71* | Male | DM, paraneoplastic | 46 | 13 | NA | Yes | No | No | Previous (46 PY) | / |
| 4 | 78 | Female | DM | 198 | 0.6 | ANF (1/80) | Yes | No | Yes | Never | / |
| 5 | 44 | Female | ASS (PM) | 55 | 1 | Jo-1 (186 U/mL)NXP-2 (58 AU)Ro-52 (>240 U/mL) | Yes | Yes | Yes | Never | / |
| 6 | 77* | Female | PM | 695 | 0.7 | Ro-SSA (>240 U/mL) La-SSB (>320 U/mL) | No | No | Yes | Never | / |
| 7 | 74 | Female | DM | 101 - 124 | 1.1 | Mi-2 (76 AU) SSA-Ro-52 (64 AU) | Yes | Yes | No | Never | 2008 F + 2014 H: no erosions. |
| 8 | 67 | Female | ASS | 45 – 51 -21 | 1 | PL-12 (89 AU) SSA-Ro 52 (> 240 U/mL) | Yes | Yes | Yes | Never | 2002 H+F: no erosions. |
| 9 | 77* | Male | PM | 196 | 3.6 | ANF (1/80) | No | No | No | Previous | / |
| 10 | 75* | Male | PM | 118 | 0.4 | SSA-Ro 52 (> 240 U/mL) | Yes | Yes | No | Previous (25 PY) | 2007 H: no erosions.2007 F: erosion right MTP1 and left MTP5. |
| 11 | 68 | Male | NAM | 44 | 1 | HMGCR (74 AU) | No | No | No | Previous (20 PY) | / |
| 12 | 84 | Female | PM | <20 | 33 | SSA-Ro 52 (242 U/mL) | No | No | Yes | Never | / |
| 13 | 49 | Male | ASS (DM) | <20 | <25 AU; >340 U/mL | Jo-1 (19 AU) | Yes | Yes | No | Previous (13 PY) | 2015 H: no erosions. |
| 14 | 56* | Male | ASS (PM) | <20 | 7.1 | Jo-1 (116 U/mL) Ro/SSA (34 U/mL)U1-RNP (9.3 U/mL) | Yes | No | Yes | Previous (30 PY) |
*Patients that passed away.
ACPAs, anticitrullinated protein antibodies; ANF, anti-nuclear factor; ASS, antisynthetase syndrome; DM, dermatomyositis; F, feet; H, hands; ILD, interstitial lung disease; MTP, metatarsophalangeal joint; NAM, necrotising autoimmune myopathy; PM, polymyositis; PY, pack years; RF, rheumatoid factor;.