Table 1

Patient characteristics and IRAEs, except musculoskeletal

Patient	Age	Sex	Cancer type	Cancer stage	ICI	Best overall response to ICI	IRAEs, except MS
1	78	Male	Melanoma	IV	Nivolumab	Partial response	Vitiligo, itching
2	37	Male	Melanoma	III	Pembrolizumab (adjuvant)	No evidence of disease	Colitis
3	75	Female	Melanoma (uvea)	IV	Nivolumab	Partial response	Suspected colitis, vertigo
4	72	Female	melanoma	IV	Nivolumab/ ipilimumab*	Partial response	Vitiligo
5	73	Male	melanoma	IV	Nivolumab/ ipilimumab*	Partial response	Pneumonitis, conjunctivitis
6	79	Female	melanoma (uvea)	IV	Nivolumab/ Ipilimumab*	Stable disease	None
7	49	Male	melanoma	IV	Nivolumab	Progress	Suspected pneumonitis, pancreatitis
8	51	Male	NSCLC	IIIb	Nivolumab	Progress	None
9	65	Male	melanoma (uvea)	IV	Ipilimumab/pembrolizumab	Stable disease	Pruritus, pancreatitis
10	53	Female	melanoma	IV	Pembrolizumab	Partial response	None
11	73	Male	Melanoma	IV	Pembrolizumab	Partial response	Colitis, myasthenic symptoms
12	58	Female	NSCLC	IIIb	Nivolumab	Stable disease	None
13	60	Male	NSCLC	IIIb	Nivolumab	Stable disease	None
14	65	Male	NSCLC	IIIa	Nivolumab	Stable disease	None

*Combination therapy.
Age, refers to age at first onset of musculoskeletal IRAEs; ICI, immune checkpoint inhibitor; IRAEs, immune-related adverse events; MS, musculoskeletal; NSCLC, non-small cell lung cancer.