Association between ACPA/RF status at baseline and time to first sustained remission using Cox proportional hazards regression analysis
| Hazard Ratio (95% Confidence Interval), p-value | ||
| Unadjusted model | Adjusted model | |
| ACPA status | ||
| ACPA neg/RF neg | Ref | Ref |
| ACPA neg /RF pos | 0.86 (0.58–1.26), 0.26 | 0.82 (0.56–1.20), 0.31 |
| ACPA pos /RF neg | 1.28 (0.84–1.96), 0.44 | 1.16 (0.74–1.80), 0.52 |
| ACPA pos /RF pos | 1.42 (1.11–1.81), 0.01 | 1.30 (1.01–1.67), 0.04 |
| Female | 0.96 (0.74–1.23), 0.73 | 0.85 (0.67–1.08), 0.19 |
| Age at baseline | 0.99 (0.98–1.00), 0.02 | 0.99 (0.98–1.00), 0.01 |
| CDAI at baseline | 0.97 (0.96–0.98),<0.0001 | 0.97 (0.96–0.98),<0.0001 |
Adjusted model is adjusted for age, sex and CDAI at baseline.
Bold values indicate statistically significant.
ACPA, anticitrullinated protein antibody; CDAI, Clinical Disease Activity Index RF, rheumatoid factor.