Table 3

Sensitivity, specificity, PPV and NPV of IBP for the diagnosis of axSpA

AssessorIBP according to…Sensitivity, % (95% CI)Specificity, % (95% CI)PPV
(95% CI)
NPV
(95% CI)
LR+
(95% CI)
LR−
(95% CI)
Blinded rheumatologistGlobal evaluation81.1
(75.4 to 86.8)
43.9
(37.3 to 50.7)
53.9
(48.0 to 59.8)
74.2
(66.8 to 81.7)
1.4
(1.3 to 1.7)
0.4
(0.3 to 0.6)
Calin’s criteria79.4
(73.5 to 85.4)
25.1
(19.6 to 31.3)
46.1
(40.6 to 51.9)
60.2
(50.0 to 70.2)
1.1
(1.0 to 1.2)
0.8
(0.6 to 1.2)
Berlin criteria81.1
(75.4 to 86.8)
32.3
(26.2 to 38.6)
49.2
(43.3 to 55.0)
67.9
(58.7 to 76.7)
1.2
(1.1 to 1.3)
0.6
(0.4 to 0.8)
ASAS criteria74.4
(68.1 to 80.8)
39.5
(33.0 to 46.1)
49.8
(43.8 to 55.8)
65.7
(57.3 to 73.4)
1.2
(1.1 to 1.4)
0.6
(0.5 to 0.9)
Diagnosing rheumatologistGlobal evaluation90.0
(85.6 to 94.4)
58.7
(52.1 to 65.2)
63.8
(57.8 to 69.7)
87.9
(81.9 to 92.7)
2.2
(1.9 to 2.6)
0.2
(0.1 to 0.3)
Calin’s criteria85.0
(79.8 to 90.2)
26.9
(21.4 to 33.0)
48.4
(42.8 to 54.1)
69.0
(58.4 to 78.2)
1.2
(1.1 to 1.3)
0.6
(0.4 to 0.8)
Berlin criteria83.9
(78.5 to 89.3)
44.8
(38.2 to 51.6)
55.1
(49.0 to 61.1)
77.5
(69.7 to 84.4)
1.5
(1.3 to 1.7)
0.4
(0.2 to 0.5)
ASAS criteria83.9
(78.5 to 89.3)
35.4
(29.2 to 41.8)
51.2
(45.3 to 57.0)
73.2
(64.2 to 80.8)
1.3
(1.2 to 1.5)
0.5
(0.3 to 0.7)
PatientCalin’s criteria75.1
(68.8 to 81.5)
20.6
(15.6 to 26.3)
43.3
(37.7 to 49.0)
50.6
(39.8 to 61.0)
0.9
(0.8 to 1.1)
1.2
(0.8 to 1.7)
Berlin criteria86.4
(81.4 to 91.5)
18.3
(13.5 to 23.7)
46.1
(40.6 to 51.6)
62.5
(50.0 to 74.0)
1.1
(1.0 to 1.2)
0.7
(0.5 to 1.2)
ASAS criteria74.0
(67.6 to 80.5)
31.1
(25.0 to 37.6)
46.5
(40.5 to 52.4)
59.7
(50.5 to 68.7)
1.1
(0.9 to 1.2)
0.8
(0.6 to 1.1)
  • ASAS, Assessment of SpondyloArthritis international Society; IBP, inflammatory back pain; LR, likelihood ratio; NPV, negative predictive value; PPV, positive predictive value; SpA, spondyloarthritis; axSpA, axial spondyloarthritis.