Pairwise correlation between change in DAS28CRP, Krenn score, EULAR-OMERACT US combined score and RAMRIS MRI synovitis score of the RCJ of the wrist during the study
| All patients with RA All visits | ΔKrenn score | ΔLarsen score* | ΔEO US combined | ΔEO US Doppler | ΔEO US GS | ΔMRI synovitis† | ΔMRI erosions | ΔMRI BM oedema |
| ΔDAS28CRP | r=0.25 p=0.12 | r=0.18 p=0.29 | r=0.38 p=0.02 | r=0.45 p=0.004 | r=0.35 p=0.02 | r=0.52 p=0.02 | r=−0.12 p=0.61 | r=0.34 p=0.16 |
| ΔKrenn score | – | r=0.01 p=0.95 | r=0.65 p<0.001 | r=0.51 p<0.001 | r=0.63 p<0.001 | r=0.50 p=0.03 | r=−0.20 p=0.39 | r=0.14 p=0.55 |
| ΔLarsen score* | – | r=0.06 p=0.71 | r=−0.04 p=0.81 | r=0.05 p=0.77 | r=0.14 p=0.58 | r=0.06 p=0.82 | r=0.06 p=0.81 | |
| ΔEO US combined | – | r=0.66 p<0.001 | r=0.96 p<0.001 | r=0.59 p<0.001 | r=−0.52 p=0.02 | r=−0.11 p=0.67 | ||
| ΔEO US Doppler | – | r=0.62 p<0.001 | r=0.61 p=0.005 | r=−0.38 p=0.09 | r=0.07 p=0.76 | |||
| ΔEO US GS | – | r=0.67 p=0.001 | r=−0.53 p=0.02 | r=−0.08 p=0.74 | ||||
| ΔMRI synovitis† | – | r=−0.27 p=0.24 | r=−0.15 p=0.54 | |||||
| ΔMRI erosions | – | r=0.00 p=1.00 |
ΔChange between 6-month visit and baseline visit data.
Comparison by unadjusted linear regression.
*Total Larsen wrist score (all quadrants).
†Only the ERA group underwent two MRI scans. Significant correlations in bold.
BM, bone marrow; EO, EULAR-OMERACT;ERA, early rheumatoid arthritis; GS, grey scale; RCJ, radiocarpal joint; US, ultrasound.